Evidence map›Paper›PMID 32741215›Full record

ArticleCartilage2021

The Role of Magnetic Resonance Imaging in Autologous Matrix-Induced Chondrogenesis for Osteochondral Lesions of the Talus: Analyzing MOCART 1 and 2.0.

Fabio A Casari, Christoph Germann, Lizzy Weigelt, Stephan Wirth, Arnd Viehöfer, Jakob Ackermann

Open access · bronzeAbstract read
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Reliability of the MOCART score: a systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
    Pooled it
  2. A randomized controlled trial demonstrating sustained benefit of autologous matrix-induced chondrogenesis (AMICEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
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  8. Correlation between EFAS- and MOCART score and clinical outcome after AMICArchives of orthopaedic and trauma surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fabio A CasariDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-9530-4861
Christoph GermannDepartment of Radiology, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-9273-0032
Lizzy WeigeltDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Stephan WirthDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Arnd ViehöferDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Jakob AckermannDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the role of magnetic resonance imaging (MRI) MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) 1 and 2.0 scores in the assessment of postoperative outcome after autologous matrix-induced chondrogenesis (AMIC) for the treatment of osteochondral lesions of the talus (OLTs). It was hypothesized that preoperative patient factors or OLT morphology are associated with postoperative MOCART scores; yet postoperative clinical outcome is not. STUDY

designCohort study; Level of evidence, 4. This study evaluated isolated AMIC that were implanted on the talus of 35 patients for the treatment of symptomatic OLT. Tegner and AOFAS (American Orthopaedic Foot and Ankle Society) scores were obtained at an average follow-up of 4.5 ± 1.8 years and postoperative MRI scored according to the MOCART 1 and 2.0.

resultsOLT size showed significant correlation with postoperative MRI scores (MOCART 1:

conclusionOsteochondral lesion size is associated with postoperative MOCART scores in patients treated with AMIC for OLTs, with decreasing MOCART scores over time. Yet clinical outcome does not correlate with any MOCART score. Thus, MOCART assessment seems to have no significant role in the postoperative treatment of asymptomatic patients that underwent AMIC for OLTs.

Indexed as

TalusChondrogenesisCohort StudiesHumansMagnetic Resonance ImagingTransplantation, AutologousAMICautologous matrix-induced chondrogenesiscartilage repairMOCARTosteoarthritisosteochondral lesiontalus

Identifiers

PMID32741215
PMCPMC8808860
OpenAlexW3046343668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.