Evidence map›Paper›PMID 32740892›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Impact of respiratory physical therapy on heart rate autonomic control in children with leukemia.

Jociele M Kirizawa, David M Garner, Vitor E Valenti

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05441670 (The Effect of a Collaborative Art Therapy and Physical Therapy Intervention on Children Undergoing a Hematopoietic Cell Transplant), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05441670 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

The Effect of a Collaborative Art Therapy and Physical Therapy Intervention on Children Undergoing a Hematopoietic Cell Transplant (HCT): a Randomized Clinical Trial

TypeinterventionalSponsorMedical University of South CarolinaRan2022 to 2026Enrolled18ConditionsHematopoietic Stem Cell Transplantation, Art Therapy, Physical TherapyArmsArt and Physical Therapy, Physical Therapy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jociele M KirizawaAutonomic Nervous System Center, Sao Paulo State University, UNESP, Av. Hygino Muzzi Filho, 737. Mirante, 17.525-900-Marília, Presidente Prudente, SP, Brazil.
David M GarnerAutonomic Nervous System Center, Sao Paulo State University, UNESP, Av. Hygino Muzzi Filho, 737. Mirante, 17.525-900-Marília, Presidente Prudente, SP, Brazil.
Vitor E ValentiAutonomic Nervous System Center, Sao Paulo State University, UNESP, Av. Hygino Muzzi Filho, 737. Mirante, 17.525-900-Marília, Presidente Prudente, SP, Brazil. vitor.valenti@unesp.br.ORCID http://orcid.org/0000-0001-7477-3805
Oxford Brookes University · GBUniversidade de Marília · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionConsidering that heart rate (HR) autonomic control is impaired in cancer and subsequent respiratory effort may overload the heart, we aimed to evaluate the effect of a respiratory physical therapy session on HR autonomic regulation in children with leukemia so as to confirm its safety.

methodsWe selected children with leukemia (n = 10) and healthy children (n = 11), which were submitted to a session of respiratory physical therapy. We used Spiron Kids (NCS, Brazil), Children's Voldyne (HUDSON RCI, USA), and Shaker (NCS, Brazil) as respiratory devices. The respiratory exercise protocols were founded on three standardized protocols. HR variability (HRV) was analyzed before, in the first minute and 5 to 10 min after intervention.

resultsWe recognized no change between rest and recovery from intervention in HRV (rMSSD-square root mean square of the differences between adjacent normal R-R intervals)-Control: p = 0.8111, Leukemia: p = 0.1197, among groups: p = 0.6574; SD1-standard deviation from instantaneous beat-to-beat variability-Control: p = 0.8111, Leukemia: p = 0.131, among groups: p = 0.6556; 0V-with no variation (3 equal symbols, for example (2,2,2)-Control: p = 0.3679, Leukemia: p = 0.3553, among groups: p = 0.7421); 2UV-with two variations to the contrary (the three symbols form a peak or a valley, for instance (3,5,3)-Control: p = 0.3679, Leukemia: p = 0.2359, among groups: p = 0.4007). HF-high frequency component, range 0.15 to 0.4 Hz-decreased 0 to 1 min after intervention in the leukemia group (p = 0.0303) and no change was observed in the control group between rest versus recovery from intervention (p = 0.9761). No significant change was reported in HF between groups (p = 0.8700). Two leukemia subjects treated with vincristine presented different HRV responses to the intervention group.

conclusionA respiratory physical therapy session did not significantly change autonomic control of HR in children with leukemia. Yet, clinicians should be mindful of subjects undergoing treatment with vincristine.

Indexed as

Autonomic Nervous SystemBrazilCase-Control StudiesChildChild, PreschoolFemaleHeart RateHumansLeukemiaMalePhysical Therapy ModalitiesProspective StudiesAutonomic nervous systemCardiovascular systemHeart rateLeukemiaPhysiotherapy

Identifiers

PMID32740892
OpenAlexW3046698364

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.