Evidence map›Paper›PMID 32740888›Full record

ArticleBrain imaging and behavior2021

Neural Modulation in Approach-Avoidance Conflicts in Externalizing Psychopathology.

Allison J Lake, Peter R Finn, Thomas W James

Open access · greenAbstract read
In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Allison J LakeDepartment of Psychiatry, Indiana University School of Medicine, 355 W. 16th St., Suite 2800, Indianapolis, IN, 46202, USA.
Peter R FinnDepartment of Psychological & Brain Sciences, Indiana University, 1101 E. 10th St, Bloomington, IN, 47405, USA.
Thomas W JamesDepartment of Psychological & Brain Sciences, Indiana University, 1101 E. 10th St, Bloomington, IN, 47405, USA. thwjames@indiana.edu.
Indiana University Bloomington · USIndiana University – Purdue University Indianapolis · US

Funding

Behavioral Disinhibition in Early-onset AlcoholismR01AA013650 · NIAAA · TRUSTEES OF INDIANA UNIVERSITY · PI FINN, PETER R · 2002 to 2018
$5.5M
INTEGRATIVE PREDOCTORAL TRAINING IN DRUG ABUSE RESEARCH AT INDIANA UNIVERSITYT32DA024628 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI Andrea Grace Hohmann, Kenneth Mackie · 2008 to 2026
$3.1M
NIAAA NIH HHS R01 AA013650NIAAA NIH HHS RO1 AA13650NIDA NIH HHS T32 DA024628
6 · The paper itself

Abstract

Externalizing psychopathology (EXT) is characterized by poor decision-making in situations that involve simultaneous cues for approach and avoidance behavior (i.e. approach-avoidance conflicts). Previous studies of EXT have examined these deficits primarily using tasks involving decisions between positive reward and negative punishment, suggesting that EXT is characterized by a general bias towards high salience (e.g. temporally proximal or reward) cues relative to low salience (e.g. temporally distal or loss) cues. However, in order to better characterize decision-making in approach-avoidance conflicts, the present study utilized a novel task to examine neural activation in contexts involving both positive reward and negative punishment as well as positive punishment and negative reward by manipulating physical proximity of affective cues. Neuroimaging results indicated that EXT was associated with deficits related to cue prioritization based on salience, suggesting that failure to differentiate relevant from less relevant information contributes to poor decision-making among individuals with EXT.

Indexed as

Decision MakingPsychopathologyCuesHumansMagnetic Resonance ImagingRewardDecision makingEmotionExternalizing psychopathologyMotivation

Identifiers

PMID32740888
PMCPMC7977936
OpenAlexW3046702700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.