Evidence map›Paper›PMID 32740887›Full record

ArticleBrain imaging and behavior2021

Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study.

Michelle R Caunca, Lily Wang, Ying Kuen Cheung, Noam Alperin, Sang H Lee, Mitchell S V Elkind, Ralph L Sacco, Clinton B Wright, Tatjana Rundek

Abstract read
In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michelle R CauncaDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.
Lily WangDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.
Ying Kuen CheungDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Noam AlperinDepartment of Radiology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Sang H LeeDepartment of Radiology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Mitchell S V ElkindDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Ralph L SaccoEvelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA.
Clinton B WrightNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Tatjana RundekEvelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA. trundek@med.miami.edu.

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGIONR01NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 1993 to 2019
$19.2M
Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
Effects of White and Gray Matter Integrity on Cognition in A Multi-Ethnic CohortF30NS103462 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CAUNCA, MICHELLE RAE · 2017 to 2020
$199k
NCATS NIH HHS KL2 TR002737NCATS NIH HHS UL1 TR002736NINDS NIH HHS F30 NS103462NINDS NIH HHS R01 NS029993NINDS NIH HHS R01 NS29993
6 · The paper itself

Abstract

High dimensional neuroimaging datasets and machine learning have been used to estimate and predict domain-specific cognition, but comparisons with simpler models composed of easy-to-measure variables are limited. Regularization methods in particular may help identify regions-of-interest related to domain-specific cognition. Using data from the Northern Manhattan Study, a cohort study of mostly Hispanic older adults, we compared three models estimating domain-specific cognitive performance: sociodemographics and APOE ε4 allele status (basic model), the basic model and MRI markers, and a model with only MRI markers. We used several machine learning methods to fit our regression models: elastic net, support vector regression, random forest, and principal components regression. Model performance was assessed with the RMSE, MAE, and R

Indexed as

Machine LearningMagnetic Resonance ImagingBiomarkersBrainCognitionCohort StudiesNeuroimagingBiomarkersBiomarkersBrain agingCognitive agingMachine learning

Identifiers

PMID32740887
PMCPMC7854979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.