ReviewReviews in endocrine & metabolic disorders2020
The role of dietary protein in obesity.
Review in Reviews in endocrine & metabolic disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Does a Higher Protein Diet Promote Satiety and Weight Loss Independent of Carbohydrate Content? An 8-Week Low-Energy Diet (LED) Intervention.Nutrients · 2022Trial
- Motives and predictors of modified Atkins diet discontinuation as treatment of adults with drug-resistant epilepsy.Epilepsia · 2026Observational
- Effects of a "5 + 2" dietary management model on body composition and behavioral modification in Chinese children with obesity: a prospective, non-randomized controlled trial.Frontiers in nutrition · 2026Article
- Long-term high-protein diet intake accelerates adipocyte senescence through macrophage CD38-mediated NADMolecular metabolism · 2026Article
- Emerging Nanonutraceuticals against Obesity.Small science · 2025Review
- The gut microbiome connects nutrition and human health.Nature reviews. Gastroenterology & hepatology · 2025Review
- The Pandora's Box of Bariatric Surgery: Unveiling the Association with Kidney Stone Risk-A Cross-Sectional Study.Obesity surgery · 2025Article
- Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men.Nature metabolism · 2025Article
- Refrigerator ownership and the nutrition-health trade-off: evidence from Chinese households.Frontiers in nutrition · 2025Article
- Comparative impact of different weight loss strategies on obstructive sleep apnea: an integrated review of surgical, pharmacological, and lifestyle interventions.Frontiers in neurology · 2025Review
- Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue.Cellular and molecular life sciences : CMLS · 2024Article
- Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.Nature metabolism · 2024Article
- Dietary proteins: from evolution to engineering.Frontiers in nutrition · 2024Review
- Association between protein-to-energy ratio and overweight/obesity in children and adolescents in the United States: a cross-sectional study based on NHANES.Frontiers in pediatrics · 2024Article
- Effectiveness of a protein-supplemented very-low-calorie diet program for weight loss: a randomized controlled trial in South Korea.Frontiers in nutrition · 2024Article
- Poultry Consumption and Human Cardiometabolic Health-Related Outcomes: A Narrative Review.Nutrients · 2023Review
- Food as Medicine for Obesity Treatment and Management.Clinical therapeutics · 2022Review
- The health effects of soy: A reference guide for health professionals.Frontiers in nutrition · 2022Review
- Efficacy of Dietary Manipulations for Depleting Intrahepatic Triglyceride Content: Implications for the Management of Non-alcoholic Fatty Liver Disease.Current obesity reports · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein-rich diets are surging in popularity for weight loss. An increase in diet-induced thermogenesis, better preservation of fat-free mass, and enhanced satiety with greater dietary protein intakes may lead to increased energy expenditure and decreased energy intake; and thus promote a more negative energy balance that facilitates weight loss. Results from large randomized trials and meta-analyses of many smaller trials indicate that high-protein diets typically induce significantly greater amounts of weight loss than conventional low-fat or high-carbohydrate diets during the early, rapid weight loss phase (3-6 months), but differences between diets are attenuated and no longer significant during the late, slow weight loss phase (12-24 months). Gradually decreasing adherence may be responsible for this observation; in fact, dietary adherence, rather than macronutrient composition, is likely the major predictor of long-term weight loss success. Recently, some randomized trials evaluated the efficacy of high-protein (vs. normal-protein) diets consumed ad libitum during weight loss maintenance, i.e. after clinically significant weight loss. Weight regain may be smaller with high-protein diets in the short-term (3-12 months), but longer studies are needed to confirm this. Given the lack of conclusive evidence in favor of high-protein diets, or any other dietary pattern, it is reasonable to conclude that no individual nutrient is a friend or a foe when it comes to weight loss and its maintenance. Therefore, any diet that best suits one's dietary habits and food preferences is likely to be better adhered to, and thus lead to more successful long-term weight loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.