Evidence map›Paper›PMID 32740787›Full record

SynthesisInternational urology and nephrology2020

Chronic kidney disease and concomitant sleep apnea are associated with increased overall mortality: a meta-analysis.

Max M Puthenpura, Panupong Hansrivijit, Nasrollah Ghahramani, Charat Thongprayoon, Wisit Cheungpasitporn

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Max M PuthenpuraDepartment of Medicine, Drexel University College of Medicine, Philadelphia, PA, 19129, USA.
Panupong HansrivijitDepartment of Internal Medicine, University of Pittsburgh Medical Center Pinnacle, 504 S. Front St, Suite 3C, Harrisburg, PA, 17104, USA. hansrivijitp@upmc.edu.ORCID http://orcid.org/0000-0002-5041-4290
Nasrollah GhahramaniDivision of Nephrology, Department of Medicine, Penn State University College of Medicine, Hershey, PA, 17033, USA.
Charat ThongprayoonDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 55905, USA.
Wisit CheungpasitpornDivision of Nephrology, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
Drexel University · USJackson Memorial Hospital · USMayo Clinic · USPennsylvania State University · USUPMC Central Pa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSleep apnea (SA) is common in advanced chronic kidney disease (CKD) patients. However, the association between CKD with concomitant SA and overall mortality remains inconclusive.

methodsOvid MEDLINE, EMBASE, and the Cochrane Library were searched for eligible publications, including non-transplant CKD patients aged > 18 years with co-existing SA. CKD is defined by estimated glomerular filtration rate of < 60 mL/min/1.73 m

resultsSeven observational studies (n = 186,686) were included in the meta-analyses. 94.2% had end-stage kidney disease (ESKD) requiring hemodialysis (HD), 5.0% had ESKD requiring peritoneal dialysis (PD), and 0.8% had non-dialysis CKD. The mean age was 76.8 ± 2.2 years. Most patients were male (53.4%) and white (76.8%). Up to 39.3% had diabetes. The mean body mass index was 26.0 ± 0.6 kg/m

conclusionCo-existence between advanced CKD and SA is associated with increased overall mortality, but not cardiovascular (CV) events when compared with CKD alone. The analysis of CV events requires additional studies to confirm our findings. Moreover, clinical interventions aiming to prevent the progression of SA and CKD are encouraged.

Indexed as

AgedFemaleHumansMaleRenal Insufficiency, ChronicSleep Apnea SyndromesChronic kidney diseaseDialysisEnd-stage kidney diseaseSleep apneaSleep-disordered breathing

Identifiers

PMID32740787
OpenAlexW3046739506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.