Evidence map›Paper›PMID 32740706›Full record

ArticleJournal of natural medicines2021

Characterization of metabolites in Saposhnikovia divaricata root from Mongolia.

Zolboo Batsukh, Kazufumi Toume, Batkhuu Javzan, Kohei Kazuma, Shao-Qing Cai, Shigeki Hayashi, Toshiyuki Atsumi, Taichi Yoshitomi, Nahoko Uchiyama, Takuro Maruyama and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Metabolite profiling of Drynariae Rhizoma usingJournal of natural medicines · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zolboo BatsukhSection of Pharmacognosy, Institute of Natural Medicine, University of Toyama, 2630, Sugitani, Toyama, 930-0194, Japan.
Kazufumi ToumeSection of Pharmacognosy, Institute of Natural Medicine, University of Toyama, 2630, Sugitani, Toyama, 930-0194, Japan. toume@inm.u-toyama.ac.jp.ORCID http://orcid.org/0000-0002-3315-145X
Batkhuu JavzanSchool of Engineering and Applied Sciences, National University of Mongolia, P.O.B-617/46A, Ulaanbaatar, 14201, Mongolia.
Kohei KazumaSection of Pharmacognosy, Institute of Natural Medicine, University of Toyama, 2630, Sugitani, Toyama, 930-0194, Japan.ORCID http://orcid.org/0000-0002-2556-7260
Shao-Qing CaiSchool of Pharmaceutical Sciences, Peking University, 38 Xue-yuan Road, Haidian District, Beijing, 100191, People's Republic of China.
Shigeki HayashiResearch Center for Medicinal Plant Resources, National Institutes of Biomedical Innovation, Health and Nutrition, 1-2 Hachimandai, Tsukuba, Ibaraki, 305-0843, Japan.
Toshiyuki AtsumiSchool of Pharmaceutical Sciences, Kyushu University of Health and Welfare, 1714-1 Yoshinocho, Nobeoka, Miyazaki, 882-8508, Japan.
Taichi YoshitomiDivision of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.
Nahoko UchiyamaDivision of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.
Takuro MaruyamaDivision of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.ORCID http://orcid.org/0000-0002-6393-3989
Nobuo KawaharaResearch Center for Medicinal Plant Resources, National Institutes of Biomedical Innovation, Health and Nutrition, 1-2 Hachimandai, Tsukuba, Ibaraki, 305-0843, Japan.
Katsuko KomatsuSection of Pharmacognosy, Institute of Natural Medicine, University of Toyama, 2630, Sugitani, Toyama, 930-0194, Japan. katsukok@inm.u-toyama.ac.jp.ORCID http://orcid.org/0000-0002-0833-7199

Funding

Japan Agency for Medical Research and Development JP17ak0101046h0002Japan Agency for Medical Research and Development JP18ak0101046h0003Japan Agency for Medical Research and Development JP19ak0101046h0004Japan Society for the Promotion of Science 15H05268Japan Society for the Promotion of Science 15K07993Japan Society for the Promotion of Science 18K06728Japan Society for the Promotion of Science 24406005
6 · The paper itself

Abstract

Saposhnikoviae Radix (SR), derived from the dried root and rhizome of Saposhnikovia divaricata, is a popular crude drug used in traditional Chinese and Japanese medicine. To evaluate the metabolites of S. divaricata roots from Mongolia and to investigate their geographical variation, we developed the HPLC method, determined the contents of 9 chromones and 4 coumarins, and conducted multivariate statistical analysis. All Mongolian specimens contained prim-O-glucosylcimifugin (1) and 4'-O-β-D-glucosyl-5-O-methylvisamminol (3), and their total amount (5.04-25.06 mg/g) exceeded the criterion assigned in the Chinese Pharmacopoeia. Moreover, the content of 1 (3.98-20.79 mg/g) was significantly higher in the Mongolian specimens than in Chinese SR samples. The specimens from Norovlin showed the highest contents of 1 and 3. The total levels of dihydropyranochromones were higher in the specimens from Bayan-Uul. The orthogonal partial least squares-discriminant analysis revealed that the Mongolian specimens tended to be separated into three groups based on growing regions, in which several chromones contributed to each distribution. Furthermore,

Indexed as

ApiaceaeMongoliaPlant Roots1H NMRHPLC–DADMongoliaMultivariate statistical analysisSaposhnikovia divaricataSaposhnikoviae Radix

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.