ArticleOptometry and vision science : official publication of the American Academy of Optometry2020
Chick Eyes Can Recover from Lens Compensation without Visual Cues.
Article in Optometry and vision science : official publication of the American Academy of Optometry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Sustained activation of Wnt/β-catenin signaling in the retina of form-deprived myopic chicks.BMC genomics · 2026Article
- Temporal properties of positive and negative defocus on emmetropization.Scientific reports · 2022Article
- Visually guided chick ocular length and structural thickness variations assessed by swept-source optical coherence tomography.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
significanceThis study shows that nonvisual mechanism(s) can guide chick eyes to recover from myopia or hyperopia bidirectionally to regain their age-matched length. Because eye growth control is phylogenetically conserved across many species, it is possible that, in general, emmetropization mechanisms are not exclusively based on a local visual feedback system. PURPOSE: Across species, growing eyes compensate for imposed defocus by modifying their growth, showing the visual controls on eye growth and emmetropization. When the spectacle lens is removed, the eyes rapidly recover back to a normal size similar to that in the untreated eyes. We asked whether this recovery process was dependent on visual feedback or whether it might be guided by intrinsic nonvisual mechanisms.
methodsChicks wore either a +7 (n = 16) or -7 D (n = 16) lens over one eye for 4 to 7 days; the fellow eye was left untreated. After lens removal, half were recovered in darkness and half in white light. Refractive error and ocular dimensions were measured before and after lens treatment and after recovery with a Hartinger refractometer and A-scan biometer, respectively.
resultsWhereas chick eyes completely recovered from prior lens treatment under normal light after 2 days, they also partially recovered from prior hyperopia (by 60%) and myopia (by 69%) after being kept in darkness for 3 days: a +7 and -7 D lens induced a difference between the eyes of +7.08 and -4.69 D, respectively. After recovery in darkness, the eyes recovered by 3.18 and 2.88 D, respectively.
conclusionsIn the absence of visual cues, anisometropic eyes can modify and reverse their growth to regain a similar length to their fellow untreated eye. Because eye growth control is phylogenetically conserved across many species, it is possible that nonvisual mechanisms may contribute more generally to emmetropization and that recovery from anisometropic refractive errors may not be wholly visually controlled.
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