Evidence map›Paper›PMID 32739818›Full record

ArticleFood chemistry2021

Treasure from garden: Bioactive compounds of buckwheat.

Md Nurul Huda, Shuai Lu, Tanzim Jahan, Mengqi Ding, Rintu Jha, Kaixuan Zhang, Wei Zhang, Milen I Georgiev, Sang Un Park, Meiliang Zhou

Registry-linked trialAbstract read
In one paragraph

Article in Food chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05234203 (The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age), which is not on this map. Cited by 84 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05234203 nacompletednot on this mapstarted 2022, after this paper: background citation

The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age

TypeinterventionalSponsorBig Bold Health, PBCRan2022 to 2022Enrolled50ConditionsImmunity Disorders, Aging, InflammationArmsHTB Rejuvenate
3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Foods (Basel, Switzerland) · 2026
    Article
  7. Buckwheat (Journal of agricultural and food chemistry · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Effects ofVirulence · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Md Nurul HudaInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Shuai LuInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Tanzim JahanDepartment of Biological Science, Faculty of Science, King Abdulaziz University, Jeddah 80208, Saudi Arabia.
Mengqi DingDepartment of Crop Science, College of Agriculture & Life Sciences, Chungnam National University, Yuseong-gu, Daejeon 305-754, Republic of Korea.
Rintu JhaInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Kaixuan ZhangInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: zhangkaixuan@caas.cn.
Wei ZhangCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Milen I GeorgievLaboratory of Metabolomics, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria; Center of Plant Systems Biology and Biotechnology, Plovdiv, Bulgaria. Electronic address: milengeorgiev@gbg.bg.
Sang Un ParkDepartment of Crop Science, College of Agriculture & Life Sciences, Chungnam National University, Yuseong-gu, Daejeon 305-754, Republic of Korea. Electronic address: supark@cnu.ac.kr.
Meiliang ZhouInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: zhoumeiliang@caas.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buckwheat is a gluten-free crop under the family Polygonaceae abundant with beneficial phytochemicals that provide significant health benefits. It is cultivated and adapted in diverse ecological zones all over the world. Recently its popularity is expanding as a nutrient-rich healthy food with low-calories. The bioactive compounds in buckwheat are flavonoids (i.e., rutin, quercetin, orientin, isoorientin, vitexin, and isovitexin), fatty acids, polysaccharides, proteins, and amino acids, iminosugars, dietary fiber, fagopyrins, resistant starch, vitamins, and minerals. Buckwheat possesses high nutritional value due to these bioactive compounds. Additionally, several essential bioactive factors that have long been gaining interest because these compounds are beneficial for healing and preventing several human diseases. The present review demonstrates an overview of the recent researches regarding buckwheat phytochemicals and particularly focusing on the distinct function of bioactive components with their health benefits.

Indexed as

ApigeninFagopyrumFlavonoidsGlucosidesHumansNutritive ValuePhytochemicalsPlant ExtractsQuercetinRutinSeedsApigeninFlavonoidsGlucosidesisovitexinorientinPhytochemicalsPlant ExtractsQuercetinRutinvitexinBuckwheatD-chiro-inositolFlavonoidsNutritional valueRutin

Identifiers

PMID32739818
PMCPMC7378508

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.