Evidence map›Paper›PMID 32739606›Full record

ReviewEuropean journal of obstetrics, gynecology, and reproductive biology2020

Sars-CoV-2 in pregnancy: Why is it better than expected?

Tullio Ghi, Elvira di Pasquo, Arsene Mekinian, Leonardo Calza, Tiziana Frusca

Open access · bronzeAbstract readReview
In one paragraph

Review in European journal of obstetrics, gynecology, and reproductive biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  6. Review
  7. Article
  8. COVID-19 and Pregnancy: A public health, evidence-based approach.Journal of the National Medical Association · 2022
    Article
  9. Article
  10. Article
  11. Pregnancy as a Risk Factor of Severe COVID-19.Journal of clinical medicine · 2021
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tullio GhiDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. Electronic address: tullio.ghi@unipr.it.
Elvira di PasquoDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy.
Arsene MekinianDepartment of Internal Medicine, Referral Center for Autoimmune Diseases, Saint Antoine Hospital, Sorbonne University, Paris, France.
Leonardo CalzaUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, Bologna, Italy.
Tiziana FruscaDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy.
University of Parma · ITSorbonne Université · FRUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the outbreak of Coronavirus disease in December 2019, information specific to pregnancy remains limited and controversial. Based on data from previous reports, it has been noticed that contrary to prior pandemics such as SARS, MERS and H1N1 and although pregnancy is usually considered as a condition of high susceptibility to viral infections, new SARS-CoV2 infection seems to have a more benign clinical course when affecting pregnant women. We speculate that during pregnancy the physiological "silencing" of the Th1 pro-inflammatory response may blunt the cytokines storm which is thought to play a key-role in the pathogenesis of the severe complications of Covid-19.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19CytokinesFemaleHumansPandemicsPneumonia, ViralPregnancyPregnancy Complications, InfectiousSARS-CoV-2CytokinesImmunologyInflammationPregnancySars-CoV-2

Identifiers

PMID32739606
PMCPMC7378463
OpenAlexW3043979081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.