Evidence map›Paper›PMID 32738898›Full record

ArticleBMC microbiology2020

Identification and characteristics of a novel cecropin from the armyworm, Mythimna separata.

Kaiqi Lian, Mingliang Zhang, Xiuli Liang, Lingling Zhou, Zhiqi Shi, Yajie Tang, Xueping Wang, Yuwei Song, Yuanchen Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kaiqi LianHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China. liankaiqi616@163.com.
Mingliang ZhangHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Xiuli LiangHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Lingling ZhouHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Zhiqi ShiHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Yajie TangHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Xueping WangHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Yuwei SongHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China.
Yuanchen ZhangHenan Joint International Research Laboratory of Veterinary Biologics Research and Application, School of Biotechnology and Food Science, Anyang Institute of Technology, No.73 Huanghe Road, Anyang, Henan, 225009, People's Republic of China. zhangyuanchen0110@163.com.
Anyang Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe recent emergence of antibiotic-resistant strains of bacteria has increased the need to develop effective alternatives to antibiotics. Antimicrobial peptides have been considered as a promising product with several advantages.

resultsIn this present study, we identified a novel cecropin from the armyworm, Mythimna separata (armyworm cecropin 1, AC-1) by transcriptome sequencing and multi-sequence alignment analysis. The AC-1 precursor comprised 63 amino acid residues, containing a conserved cleavage site of the signal peptide, Ala

conclusionsThis study identified a novel antimicrobial peptide that may represent a potential alternative to antibiotics.

Indexed as

Amino Acid SequenceAnimalsAnti-Bacterial AgentsBacteriaCecropinsCells, CulturedCell SurvivalEscherichia coliHemolysisInsect ProteinsLepidopteraProtein Sorting SignalsProtein StabilityProtein Structure, SecondaryRecombinant ProteinsSaltsAnti-Bacterial AgentsCecropinsInsect ProteinsProtein Sorting SignalsRecombinant ProteinsSaltsAntimicrobial activityAntimicrobial peptideArmywormCecropin

Identifiers

PMID32738898
PMCPMC7395354
OpenAlexW3046490506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.