Evidence map›Paper›PMID 32738167›Full record

ArticleClinical transplantation2020

Physician and patient acceptance of policies to reduce kidney discard.

Sanjay Mehrotra, Karolina Schantz, John J Friedewald, Daniela P Ladner, Yolanda Becker, Richard Formica, Masoud Barah, Jiayi Gu, Elisa J Gordon

Abstract read
In one paragraph

Article in Clinical transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Kidney organ allocation: reducing discards.Current opinion in organ transplantation · 2023
    Review
  3. Dealing With the Kidney Discard Problem in the United States-One Potential Solution for a Difficult Problem.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sanjay MehrotraDepartment of Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0003-1106-1901
Karolina SchantzDepartment of Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-5466-0536
John J FriedewaldDepartment of Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.
Daniela P LadnerComprehensive Transplant Center Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Yolanda BeckerUniversity of Chicago Medicine, Chicago, IL, USA.
Richard FormicaYale-New Haven Transplantation Center, New Haven, CT, USA.
Masoud BarahDepartment of Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0003-0953-3789
Jiayi GuDepartment of Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.
Elisa J GordonComprehensive Transplant Center Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-0969-1998

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Rescuing Kidneys at Risk of DiscardR01DK118425 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MEHROTRA, SANJAY · 2019 to 2022
$2.8M
NCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1 TR001863NIDDK NIH HHS R01 DK118425
6 · The paper itself

Abstract

Despite the shortage of kidneys for transplantation in the United States, approximately 18%-20% of deceased donor kidneys are discarded each year. These discarded kidneys can offer a survival benefit to suitable patients. Revisions to the current kidney allocation policy may be needed to reduce deceased donor kidney discard. We surveyed transplant physicians and patients to assess their perceived acceptability of policy proposals to reduce the discard of deceased donor kidneys. Members of professional societies (AST, ASTS) and a patient organization (AAKP) were invited to complete the survey. Responses were obtained from 97 physicians and 107 patients. The majority of physicians (73.4%) and patients (73.8%) "somewhat" or "completely" accepted a policy for fast-tracking kidneys at risk of discard. Physicians and patients also supported returning a proportion of waiting time to patients who accept KDPI >85 kidneys and experience graft failure within the first 12 months, with 36% of physicians and 50% of patients electing to return 100% of the waiting time. The majority of physicians (75%) "somewhat or completely" accepted a policy to skip less aggressive centers for KDPI 90 + offers. Physicians and patients provided insights into factors researchers, and policymakers should consider in the design and implementation of these policies.

Indexed as

Kidney TransplantationPhysiciansTissue and Organ ProcurementDonor SelectionGraft SurvivalHumansKidneyPolicyRisk FactorsTissue DonorsUnited Statesethicskidney allocationkidney transplantationpolicy

Identifiers

PMID32738167
PMCPMC7929781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.