Evidence map›Paper›PMID 32738091›Full record

ArticleMagnetic resonance in medicine2021

A novel sequence for simultaneous measurement of whole-brain static and dynamic MRA, intracranial vessel wall image, and T

Zhensen Chen, Zechen Zhou, Haikun Qi, Huijun Chen, Baocheng Chu, Thomas S Hatsukami, Chun Yuan, Niranjan Balu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Zhensen ChenVascular Imaging Lab and BioMolecular Imaging Center, Department of Radiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-7975-2528
Zechen ZhouPhilips Research North America, Cambridge, Massachusetts, USA.ORCID 0000-0001-8149-7546
Haikun QiSchool of Biomedical Engineering & Imaging Science, King's College London, London, United Kingdom.
Huijun ChenCenter for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, People's Republic of China.ORCID 0000-0003-1158-5510
Baocheng ChuVascular Imaging Lab and BioMolecular Imaging Center, Department of Radiology, University of Washington, Seattle, Washington, USA.
Thomas S HatsukamiDepartment of Surgery, University of Washington, Seattle, Washington, USA.
Chun YuanVascular Imaging Lab and BioMolecular Imaging Center, Department of Radiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-6154-5106
Niranjan BaluVascular Imaging Lab and BioMolecular Imaging Center, Department of Radiology, University of Washington, Seattle, Washington, USA.
University of Washington · USKing's College London · GBPhilips (United States) · USTsinghua University · CN

Funding

Carotid Intraplaque Hemorrhage: MRI of Therapeutic Response and Clinical SequelaeR01HL103609 · NHLBI · UNIVERSITY OF WASHINGTON · PI HATSUKAMI, THOMAS, YUAN, CHUN · 2011 to 2021
$7.1M
3D WALLI: MR intracranial vessel wall imaging for stroke preventionR01NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2016 to 2019
$3.1M
NHLBI NIH HHS R01 HL103609NINDS NIH HHS R01 NS092207
6 · The paper itself

Abstract

purposeTo propose a highly time-efficient imaging technique named improved simultaneous noncontrast angiography and intraplaque hemorrhage (iSNAP) for simultaneous assessment of lumen, vessel wall, and blood flow in intracranial arteries.

methodsiSNAP consists of pulsed arterial spin labeling preparations and 3D golden angle radial acquisition. Images were reconstructed by k-space weighted image contrast (KWIC) method with optimized data-sharing strategies. Dynamic MRA for blood flow assessment was obtained from iSNAP by reconstruction at multiple inversion times and image subtraction, static MRA by both image subtraction approach and phase-sensitive inversion recovery technique, and vessel wall images by both reconstruction at zero-crossing time-point of blood and phase-sensitive inversion recovery. A T

resultsiSNAP has whole-brain coverage and takes ~6.5 min. The dedicated reconstruction strategies are feasible for each iSNAP image contrast and beneficial for image SNR. iSNAP-dynamic MRA yields similar dynamic flow information as 4D-TRANCE and allows more flexible temporal resolution. The 2 types of iSNAP static MRA images complement each other in characterizing both proximal large arteries and distal small arteries. Depiction of vessel wall lesions in iSNAP vessel wall images is better than SNAP and may be similar to T

conclusioniSNAP provides a time-efficient evaluation of intracranial arteries and may have great potential for comprehensive assessment of intracranial vascular conditions using a single sequence.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance AngiographyBrainHumansMagnetic Resonance ImagingSpin LabelsSpin Labelsblood flowdynamic MRAintracranialiSNAPMRAvessel wall

Identifiers

PMID32738091
PMCPMC7722084
OpenAlexW3046853177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.