Evidence map›Paper›PMID 32738084›Full record

ArticleMagnetic resonance in medicine2021

TURBINE-MRE: A 3D hybrid radial-Cartesian EPI acquisition for MR elastography.

Yi Sui, Arvin Arani, Joshua D Trzasko, Matthew C Murphy, Phillip J Rossman, Kevin J Glaser, Kiaran P McGee, Armando Manduca, Richard L Ehman, Philip A Araoz and 1 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yi SuiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-8177-1661
Arvin AraniDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Joshua D TrzaskoDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Matthew C MurphyDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Phillip J RossmanDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Kevin J GlaserDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Kiaran P McGeeDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Armando ManducaDepartment of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-9411-5671
Richard L EhmanDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Philip A AraozDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
John HustonDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

High-performance compact 3T MRI: Technical optimization for advanced brain imagingU01EB024450 · NIBIB · MAYO CLINIC ROCHESTER · PI BERNSTEIN, MATTHEW A., FOO, THOMAS K · 2017 to 2021
$5.3M
Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)R01EB017197 · NIBIB · MAYO CLINIC ROCHESTER · PI YIN, MENG · 2014 to 2025
$4.3M
Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
NIBIB NIH HHS R01 EB017197NIBIB NIH HHS R37 EB001981NIBIB NIH HHS U01 EB024450
6 · The paper itself

Abstract

purposeTo develop a novel magnetic resonance elastography (MRE) acquisition using a hybrid radial EPI readout scheme (TURBINE), and to demonstrate its feasibility to obtain wave images and stiffness maps in a phantom and in vivo brain.

methodThe proposed 3D TURBINE-MRE is based on a spoiled gradient-echo MRE sequence with the EPI readout radially rotating about the phase-encoding axis to sample a full 3D k-space. A polyvinyl chloride phantom and 6 volunteers were scanned on a compact 3T GE scanner with a 32-channel head coil at 80 Hz and 60 Hz external vibration, respectively. For comparison, a standard 2D, multislice, spin-echo (SE) EPI-MRE acquisition was also performed with the same motion encoding and resolution. The TURBINE-MRE images were off-line reconstructed with iterative SENSE algorithm. The regional ROI analysis was performed on the 6 volunteers, and the median stiffness values were compared between SE-EPI-MRE and TURBINE-MRE.

resultsThe 3D wave-field images and the generated stiffness maps were comparable between TURBINE-MRE and standard SE-EPI-MRE for the phantom and the volunteers. The Bland-Altman plot showed no significant difference in the median regional stiffness values between the two methods. The stiffness measured with the 2 methods had a strong linear relationship with a Pearson correlation coefficient of 0.943.

conclusionWe demonstrated the feasibility of the new TURBINE-MRE sequence for acquiring the desired 3D wave-field data and stiffness maps in a phantom and in-vivo brains. This pilot study encourages further exploration of TURBINE-MRE for functional MRE, free-breathing abdominal MRE, and cardiac MRE applications.

Indexed as

Elasticity Imaging TechniquesEcho-Planar ImagingHumansMagnetic Resonance ImagingPilot ProjectsReproducibility of ResultsMR elastographyradial acquisitionTURBINE

Identifiers

PMID32738084
PMCPMC7722069
OpenAlexW3046713522

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.