ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021
Effects of Vocal Training on Thyroarytenoid Muscle Neuromuscular Junctions and Myofibers in Young and Older Rats.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Interrogating roles for VTA dopamine neurons in locomotion and ultrasonic vocalizations elicited by different classes of rewarding drugs.Psychopharmacology · 2026Article
- The evidence for old age motor neuron death: A scoping review.Physiological reports · 2026Article
- Ultrasonic Vocalization Acoustics After Recurrent Laryngeal Nerve Injury and Recovery.The Laryngoscope · 2025Article
- The role of ultrasonic vocalizations in rat laryngological investigations.Physiology & behavior · 2025Review
- Potential Biophysiological Mechanisms Underlying Vocal Demands and Vocal Fatigue.Journal of voice : official journal of the Voice Foundation · 2025Review
- Rehabilitation Treatment Specification System: Content and Criterion Validity Across Evidence-Based Voice Therapies for Muscle Tension Dysphonia.American journal of speech-language pathology · 2024Article
- Rats that learn to vocalize for food reward emit longer and louder appetitive calls and fewer short aversive calls.PloS one · 2024Review
- Changes in ultrasonic vocalizations after unilateral cerebral ischemia in a rat stroke model.Behavioural brain research · 2023Article
- Metabolomic Expression of Laryngeal and Hindlimb Muscles in Adult versus Senescent Rats.The Annals of otology, rhinology, and laryngology · 2022Article
- Manipulation of vocal communication and anxiety through pharmacologic modulation of norepinephrine in the Pink1-/- rat model of Parkinson disease.Behavioural brain research · 2022Article
- Semi-Automated Training of Rat Ultrasonic Vocalizations.Frontiers in behavioral neuroscience · 2022Article
- Proteomic Characterization of Senescent Laryngeal Adductor and Plantaris Hindlimb Muscles.The Laryngoscope · 2022Article
- Biological and Acoustic Sex Differences in Rat Ultrasonic Vocalization.Brain sciences · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this investigation was to determine the effects of vocal training on neuromuscular junction (NMJ) morphology and muscle fiber size and composition in the thyroarytenoid muscle, the primary muscle in the vocal fold, in younger (9-month) and older (24-month) Fischer 344 × Brown Norway male rats. Over 4 or 8 weeks of vocal training, rats of both ages progressively increased their daily number of ultrasonic vocalizations (USVs) through operant conditioning and were then compared to an untrained control group. Neuromuscular junction morphology and myofiber size and composition were measured from the thyroarytenoid muscle. Acoustic analysis of USVs before and after training quantified the functional effect of training. Both 4- and 8-week training resulted in less NMJ motor endplate dispersion in the lateral portion of the thyroarytenoid muscle in rats of both ages. Vocal training and age had no significant effects on laryngeal myofiber size or type. Vocal training resulted in a greater number of USVs with longer duration and increased intensity. This study demonstrated that vocal training induces laryngeal NMJ morphology and acoustic changes. The lack of significant effects of vocal training on muscle fiber type and size suggests vocal training significantly improves neuromuscular efficiency but does not significantly influence muscle strength changes.
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Registered trials
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