Evidence map›Paper›PMID 32737968›Full record

ArticlePhysical therapy2020

Magnetic Resonance Imaging Studies in Duchenne Muscular Dystrophy: Linking Findings to the Physical Therapy Clinic.

Claudia R Senesac, Alison M Barnard, Donovan J Lott, Kavya S Nair, Ann T Harrington, Rebecca J Willcocks, Kirsten L Zilke, William D Rooney, Glenn A Walter, Krista Vandenborne

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Physical therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01484678 (Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01484678 recruitingnot on this map

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

TypeobservationalSponsorUniversity of FloridaRan2020 to 2026Enrolled550ConditionsDuchenne Muscular Dystrophy, Becker Muscular Dystrophy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Claudia R SenesacDepartment of Physical Therapy, University of Florida, Box 100154, UFHSC, Gainesville, FL 32610-0154 (USA).
Alison M BarnardDepartment of Physiology and Functional Genomics, University of Florida.
Donovan J LottDepartment of Physical Therapy, University of Florida.
Kavya S NairDepartment of Physical Therapy, University of Florida.
Ann T HarringtonCenter for Rehabilitation, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; and Department of Physical Therapy, Arcadia University, Glenside, Pennsylvania.
Rebecca J WillcocksDepartment of Physical Therapy, University of Florida.
Kirsten L ZilkeOregon Health & Science University, Shriners Hospitals for Children, Portland, Oregon.
William D RooneyAdvanced Imaging Research Center, Oregon Health & Science University.
Glenn A WalterDepartment of Physiology and Functional Genomics, University of Florida.
Krista VandenborneDepartment of Physical Therapy, University of Florida.
University of Florida · USAdvanced Imaging Research (United States) · USArcadia University · USOregon Health & Science University · US

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
Magnetic Resonance Imaging and Biomarkers for Muscular DystropyR01AR056973 · NIAMS · UNIVERSITY OF FLORIDA · PI VANDENBORNE, KRISTA H · 2010 to 2024
$20.2M
Breathing Research and Therapeutics (BREATHE)T32HL134621 · NHLBI · UNIVERSITY OF FLORIDA · PI Gordon S. Mitchell · 2017 to 2026
$3.4M
NHLBI NIH HHS T32 HL134621NIAMS NIH HHS R01 AR056973NIAMS NIH HHS U54 AR052646
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a muscle degenerative disorder that manifests in early childhood and results in progressive muscle weakness. Physical therapists have long been an important component of the multidisciplinary team caring for people with DMD, providing expertise in areas of disease assessment, contracture management, assistive device prescription, and exercise prescription. Over the last decade, magnetic resonance imaging of muscles in people with DMD has led to an improved understanding of the muscle pathology underlying the clinical manifestations of DMD. Findings from magnetic resonance imaging (MRI) studies in DMD, paired with the clinical expertise of physical therapists, can help guide research that leads to improved physical therapist care for this unique patient population. The 2 main goals of this perspective article are to (1) summarize muscle pathology and disease progression findings from qualitative and quantitative muscle MRI studies in DMD and (2) link MRI findings of muscle pathology to the clinical manifestations observed by physical therapists with discussion of any potential implications of MRI findings on physical therapy management.

Indexed as

Magnetic Resonance ImagingPhysical Therapy ModalitiesChildDisease ProgressionHumansMaleMuscle, SkeletalMuscle WeaknessMuscular Dystrophy, DuchenneMuscle WeaknessMuscular DystroophiesNeuromuscular Diseases

Identifiers

PMID32737968
PMCPMC7596892
OpenAlexW3046566832

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.