Evidence map›Paper›PMID 32737953›Full record

ArticleHead & neck2020

Primary tumor volume as a predictor of distant metastases and survival in patients with sinonasal mucosal melanoma.

Stephanie Flukes, Shivangi Lohia, Christopher A Barker, Jennifer R Cracchiolo, Ian Ganly, Snehal G Patel, Benjamin R Roman, Jatin P Shah, Alexander N Shoushtari, Viviane Tabar and 2 more

Abstract read
In one paragraph

Article in Head & neck, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Impact of Primary Tumor Volume on Survival of Patients with Non-Surgically Treated Advanced-Stage Hypopharyngeal Cancer- Retrospective Study and Literature Overview.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stephanie FlukesDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-9312-9409
Shivangi LohiaDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-2335-3581
Christopher A BarkerDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jennifer R CracchioloDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-4496-906X
Ian GanlyDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Snehal G PatelDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Benjamin R RomanDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jatin P ShahDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-6444-6592
Alexander N ShoushtariDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Viviane TabarDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Akash ShahDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Marc A CohenDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-6104-7967

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundSinonasal mucosal melanoma (SNMM) is an aggressive cancer with high mortality. Identifying patients at risk of distant metastasis assists with management and prognostication. We aimed to define the relationship between volume, survival, and risk of distant metastases.

methodsA retrospective review of all patients with SNMM treated at a single institution over a 21-year period was conducted. Tumor volume was calculated using cross-sectional imaging and survival analysis was performed.

resultsSixty-one patients were included. Tumor volume was predictive of local progression-free survival (P = .03), distant metastases-free survival (DMFS) (P = .002), and overall survival (OS) (P = .02). It was a better predictor than AJCC stage and T-classification. Tumor volume equal to or greater than 5 cm

conclusionCalculation of tumor volume assists in quantifying the risk of distant metastases and death in SNMM.

Indexed as

MelanomaParanasal Sinus NeoplasmsHumansNasal MucosaNeoplasm StagingPrognosisRetrospective StudiesSurvival RateTumor Burdenmucosal melanomasinonasalstaging systemssurvivaltumor volume

Identifiers

PMID32737953
PMCPMC7722123

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.