ReviewHepatology (Baltimore, Md.)2020
Functional Role of the Secretin/Secretin Receptor Signaling During Cholestatic Liver Injury.
Open access · bronzeAbstract readReview
In one paragraph
Review in Hepatology (Baltimore, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Structural and Hormonal Changes Associated With Starvation in Zambian Adult Patients With Esophageal Strictures: A Cross-Sectional Study.Health science reports · 2026Article
- The Role of FGF1 in Chronic Liver Diseases.Biomedicines · 2026Review
- Targeting the Secretin Receptor in Macrophages Attenuates Silica-Induced Pulmonary Fibrosis.Cell proliferation · 2025Article
- Advances in prognostic biomarkers for biliary atresia: Current insights and future directions.Journal of pediatric gastroenterology and nutrition · 2025Review
- Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitis.Nature communications · 2024Article
- Unraveling the complexities of fibrosis and ductular reaction in liver disease: pathogenesis, mechanisms, and therapeutic insights.American journal of physiology. Cell physiology · 2024Review
- Sequence of events leading to primary biliary cholangitis.World journal of gastroenterology · 2023Review
- Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity.Cell & bioscience · 2023Article
- Peptidomic Approaches and Observations in Neurodegenerative Diseases.International journal of molecular sciences · 2022Review
- Liver secretin receptor predicts portoenterostomy outcomes and liver injury in biliary atresia.Scientific reports · 2022Article
- Role of YAP1 Signaling in Biliary Development, Repair, and Disease.Seminars in liver disease · 2022Review
- Recent discoveries in microbiota dysbiosis, cholangiocytic factors, and models for studying the pathogenesis of primary sclerosing cholangitis.Open medicine (Warsaw, Poland) · 2022Review
- Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?Cells · 2021Review
- Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19.Cell death & disease · 2021Article
- Cholangiocarcinoma: bridging the translational gap from preclinical to clinical development and implications for future therapy.Expert opinion on investigational drugs · 2021Review
- Biliary Epithelial Senescence in Liver Disease: There Will Be SASP.Frontiers in molecular biosciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 2 countries.
Nan Wu *Hepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Leonardo Baiocchi *Liver Unit, Department of Medicine, University of Rome "Tor Vergata,", Rome, Italy.
Tianhao ZhouDepartment of Medical Physiology, Texas A&M University, Bryan, TX.
Lindsey KennedyHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Ludovica CeciHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Fanyin MengHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Keisaku SatoHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Chaodong WuDepartment of Nutrition, Texas A&M University, College Station, TX.
Burcin EkserDivision of Transplant Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.ORCID 0000-0003-0741-8007
Konstantina KyritsiHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.ORCID 0000-0002-7424-2788
Debjyoti KunduHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Lixian ChenHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Vik MeadowsHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Antonio FranchittoEleonora Lorillard Spencer Cenci Foundation, Rome, Italy.
Domenico AlvaroDepartment of Internal Medicine and Medical Specialties, Rome, Italy.
Paolo OnoriDepartment of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy.
Eugenio GaudioDepartment of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy.
Ilaria LenciLiver Unit, Department of Medicine, University of Rome "Tor Vergata,", Rome, Italy.
Heather FrancisHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Shannon GlaserDepartment of Medical Physiology, Texas A&M University, Bryan, TX.
Gianfranco AlpiniHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN.
Indiana University Health · USSapienza University of Rome · ITTexas A&M Health Science Center · USUniversity of Rome Tor Vergata · ITIndiana University School of MedicineSurgical Specialties (United States) · USTexas A&M University · US
Funding
GROWTH REGULATION OF THE INTRAHEPATIC BILIARY TREER01DK054811 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2000 to 2021
$3.8MThe Paracrine Regulation of Mast Cells During Biliary/Cholangiocyte Repair and DamageR01DK108959 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI FRANCIS, HEATHER L · 2016 to 2024
$2.5MRegulation of Bile Duct Growth in Bile Duct Ligated RatsR01DK062975 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2005 to 2014
$1.9MRole of Sensory Neuropeptides in the Regulation of Biliary FunctionR01DK076898 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2008 to 2016
$1.8MThe Role of Stem Cell Derived Microvesicles in Cholestatic Liver InjuryR01DK107310 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2015 to 2019
$1.7MMechanisms of mast cell/cholangiocyte regulation of non-alcoholic fatty liver disease progressionR01DK119421 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI FRANCIS, HEATHER L · 2019 to 2022
$1.4MNeuroendocrine Regulation of Biliary Growth and FibrosisR01DK110035 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2017 to 2020
$1.2MRegulation of biliary growth and fibrosis by melatoninR01DK115184 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2017 to 2020
$1.2MREGULATION OF CELLULAR SENESCENCE BY NON-CODING RNAS IN ALCOHOLIC LIVER INJURYR21AA025997 · NIAAA · SCOTT AND WHITE MEMORIAL HOSPITAL · PI ALPINI, GIANFRANCO D, MENG, FANYIN · 2017 to 2018
$435kRole of stem cell derived microvesicles in alcoholic liver injuryR21AA025157 · NIAAA · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, MENG, FANYIN · 2017 to 2018
$350kBLR&D Research Career Scientist AwardIK6BX004601 · VA · RLR VA MEDICAL CENTER · PI ALPINI, GIANFRANCO D · 2019 to 2025
–Autocrine/Paracrine Regulation of Intrahepatic Bile Duct GrowthI01BX000574 · VA · RLR VA MEDICAL CENTER · PI ALPINI, GIANFRANCO D · 2009 to 2022
–BLRD VA I01 BX000574BLRD VA I01 BX001724BLRD VA I01 BX003031BLRD VA IK6 BX004601BLRD VA IK6 BX005226NIAAA NIH HHS R21 AA025157NIAAA NIH HHS R21 AA025997NIDDK NIH HHS R01 DK054811NIDDK NIH HHS R01 DK062975NIDDK NIH HHS R01 DK076898NIDDK NIH HHS R01 DK107310NIDDK NIH HHS R01 DK108959NIDDK NIH HHS R01 DK110035NIDDK NIH HHS R01 DK115184NIDDK NIH HHS R01 DK119421
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsBileBile Acids and SaltsBile DuctsCholestasisChronic DiseaseDisease Models, AnimalEpitheliumHumansLiverReceptors, Gastrointestinal HormoneReceptors, G-Protein-CoupledSecretinSignal TransductionBile Acids and SaltsReceptors, Gastrointestinal HormoneReceptors, G-Protein-CoupledSecretinsecretin receptor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.