ArticleBrain imaging and behavior2021
Neurobiological effects of perceived stress are different between adolescents and middle-aged adults.
Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Training with Different Modes of Strength Intervention on Psychosocial Disorders in Adolescents: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Family Environmental Risk and Perceived Stress in Adolescent Depressive Symptoms: A Network Analysis.Child psychiatry and human development · 2026Article
- Perceived stress mediates the association between orbitofrontal cortex grey matter volume and depressive symptoms in older women.Scientific reports · 2025Article
- Childhood adversities and suicidal ideation among young adults with serious mental illnesses: The mediating roles of perceived stress, dispositional hope, and mental health hope.Journal of affective disorders · 2025Article
- Epigenome-wide association study of long-term psychosocial stress in older adults.Epigenetics · 2024Article
- Interaction of perceived social support and childhood maltreatment on limbic responsivity towards negative emotional stimuli in healthy individuals.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Perceived Stress From Childhood to Adulthood and Cardiometabolic End Points in Young Adulthood: An 18-Year Prospective Study.Journal of the American Heart Association · 2024Article
- The double-edged sword of the hippocampus-ventromedial prefrontal cortex resting-state connectivity in stress susceptibility and resilience: A prospective study.Neurobiology of stress · 2023Article
- Article
- Parental psychosocial factors predicting adolescents' psychological adjustment during the surging and remission periods of COVID-19 in China: A longitudinal study.Journal of affective disorders · 2023Article
- Adverse childhood experiences and perceived stress in early adulthood in the context of disadvantage.Child abuse & neglect · 2022Article
- Higher Peripheral Inflammation Is Associated With Lower Orbitofrontal Gamma Power in Chronic Tinnitus.Frontiers in behavioral neuroscience · 2022Article
- Artificial neural network application for identifying risk of depression in high school students: a cross-sectional study.BMC psychiatry · 2021Article
- Commercial Off-The-Shelf Video Games for Reducing Stress and Anxiety: Systematic Review.JMIR mental health · 2021Review
- Amygdala size varies with stress perception.Neurobiology of stress · 2021Article
- Implications of COVID-19 and Lockdown on Internet Addiction Among Adolescents: Data From a Developing Country.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Stress is an inevitable element of everyday living. Developmental studies suggested that adolescents are more vulnerable and sensitive to the effect of stress due to their developing brains, especially in areas related to stress perception and processing. This voxel-based morphometry study examined the association between various neurobiological markers and the level of perceived stress experienced by adolescents (n = 26) and middle-aged adults (n = 26). Our findings indicated that differences existed in the relationships between perceived stress and the structural volume of the orbitofrontal cortex (OFC) extending to the insula and amygdala. Specifically, the levels of perceived stress and the grey matter volume of the orbitofrontal cortex, the insula, and the amygdala were positively related in adolescents but negatively related for adults. Furthermore, a significant negative correlation between perceived stress and cortisol levels was observed in adults, whereas the relationship between perceived stress and cortisol levels was not significant for adolescents. Perceived stress measurement may be better than cortisol levels in terms of reflecting the emotional states of adolescents. In sum, the relationships between perceived stress and neurobiological markers were different between adolescents and middle-aged adults and thus appeared to be age dependent.
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