Evidence map›Paper›PMID 32737732›Full record

ArticleInternational ophthalmology2020

Surgical outcomes in patients with optic disc pit maculopathy: does peeling the ILM lead to better outcomes?

Helena Wagner, Amelie Pielen, Hansjürgen Agostini, Daniel Böhringer, Wolf Alexander Lagrèze, Julia Biermann

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Helena WagnerEye Center at Medical Center, University of Freiburg, Killianstrasse 5, Freiburg, Germany.
Amelie PielenHannover Medical School, University Eye Hospital, Carl-Neuberg-Str. 1, Hannover, Germany.
Hansjürgen AgostiniEye Center at Medical Center, University of Freiburg, Killianstrasse 5, Freiburg, Germany.
Daniel BöhringerEye Center at Medical Center, University of Freiburg, Killianstrasse 5, Freiburg, Germany.
Wolf Alexander LagrèzeEye Center at Medical Center, University of Freiburg, Killianstrasse 5, Freiburg, Germany.
Julia BiermannEye Center at Medical Center, University of Freiburg, Killianstrasse 5, Freiburg, Germany. julia.biermann@ukmuenster.de.ORCID http://orcid.org/0000-0001-5510-3857
University of Freiburg · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOptic disc pits (ODPs) are rare congenital anomalies. Several patients develop optic disc pit maculopathy (ODP-M): visual impairment caused by intra- and/or subretinal fluid. Treatment mode remains controversial. This study was designed to investigate the effectiveness of pars plana vitrectomy (PPV) and gas tamponade with or without internal limiting membrane (ILM)-peeling in improving visual acuity and reducing subretinal fluid in ODP-M patients.

methodsWe retrospectively reviewed the charts of 16 patients who underwent surgery for ODP-M from 2002-2015. Six patients underwent PPV with gas tamponade (group 1); ten patients additionally received ILM-peeling (group 2). Pre- and postoperative visual acuity and central retinal thickness (CRT) were compared between groups, as well as retinal morphology and the number of secondary vitrectomies and complications.

resultsMedian visual acuity improved by 2 ETDRS lines in both groups (p = 0.713, Mann-Whitney U test). Median CRT decreased by 426.5 µm and 460 µm (p = 0.931). One patient in group 1 underwent repeat vitrectomy for persistent retinoschisis. Three patients in group 2 required repeat vitrectomy: two to treat a macular hole, one for peripheral retinal holes with retinal detachment.

conclusionIn our cohort, PPV with gas tamponade proved to be an effective first-line treatment for ODP-M. Additional ILM-peeling did not give a significant benefit in this study.

Indexed as

Macular DegenerationOptic DiskFollow-Up StudiesHumansRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVitrectomyGas tamponadeILM-peelingMaculopathyOptic disc pitPars plana vitrectomy

Identifiers

PMID32737732
PMCPMC8370961
OpenAlexW3046783460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.