Evidence map›Paper›PMID 32737614›Full record

ArticleEuropean journal of nutrition2021

Mediterranean diet, alcohol-drinking pattern and their combined effect on all-cause mortality: the Seguimiento Universidad de Navarra (SUN) cohort.

Gladys Morales, Miguel A Martínez-González, María Barbería-Latasa, Maira Bes-Rastrollo, Alfredo Gea

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In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gladys MoralesDepartamento de Salud Pública, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.ORCID http://orcid.org/0000-0001-7194-8833
Miguel A Martínez-GonzálezDepartment of Preventive Medicine and Public Health, IdisNA, University of Navarra, Pamplona, Spain.
María Barbería-LatasaDepartment of Preventive Medicine and Public Health, IdisNA, University of Navarra, Pamplona, Spain.
Maira Bes-RastrolloDepartment of Preventive Medicine and Public Health, IdisNA, University of Navarra, Pamplona, Spain. mbes@unav.es.ORCID http://orcid.org/0000-0002-9139-4206
Alfredo GeaDepartment of Preventive Medicine and Public Health, IdisNA, University of Navarra, Pamplona, Spain.

Funding

Departamento de Educación, Gobierno de Navarra 27/2011, 45/2011, 122/2014Instituto de Salud Carlos III RD 06/0045, CIBER-OBN, Grants PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, and G03/140
6 · The paper itself

Abstract

purposeThe health benefits of the Mediterranean diet (MedDiet) have been widely studied. However, controversy remains for one of its components: alcohol intake. We aimed to assess the joint effect of adherence to the MedDiet and alcohol-drinking pattern on all-cause mortality.

methodsWe used data from 20,506 subjects from a prospective cohort of Spanish university graduates, the Seguimiento Universidad de Navarra (SUN) cohort. Adherence to the MedDiet was operationalized using four different dietary indexes and then categorized in low or high adherence, according to the median score. Alcohol-drinking pattern was evaluated with the previously defined the Mediterranean alcohol-drinking pattern (MADP), grouped into three categories of adherence (low, moderate and high adherence) and a fourth category for abstainers. The outcome was all-cause mortality.

resultsDuring a median follow-up of 12.1 years, we observed 460 deaths. No statistically significant supra-multiplicative interaction between the two exposures was found. Low adherence to both the MedDiet and MADP was associated with higher all-cause mortality compared to high adherence to both exposures [multivariable-adjusted hazard ratio (HR) = 2.02, 95% confidence interval (CI): 1.33-3.07]. Similar results were found for cancer mortality and cardiovascular mortality.

conclusionsAlthough the combined effect of the MedDiet and MADP was not significantly higher than the product of their individual effects, a low adherence to both the MedDiet and MADP was associated with higher rates of all-cause mortality. This report also shows the usefulness of the dietary pattern approach applied to alcohol intake and of including the drinking pattern as another component of the MedDiet.

Indexed as

Diet, MediterraneanCohort StudiesHealth BehaviorHumansProportional Hazards ModelsProspective StudiesSpainAlcoholCancer mortalityCardiovascular mortalityInteractionNutritionProspective

Identifiers

PMID32737614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.