Evidence map›Paper›PMID 32737558›Full record

ArticleWorld journal of surgery2020

Risk Factors for Prolonged Length of Stay and Readmission After Parathyroidectomy for Renal Secondary Hyperparathyroidism.

Dessislava Stefanova, Timothy M Ullmann, Jessica Limberg, Maureen Moore, Toni Beninato, Rasa Zarnegar, Thomas J Fahey, Brendan M Finnerty

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Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dessislava StefanovaDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0003-2460-9235
Timothy M UllmannDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Jessica LimbergDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Maureen MooreDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Toni BeninatoDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Rasa ZarnegarDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Thomas J FaheyDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA.
Brendan M FinnertyDepartment of Surgery, Weill Cornell Medical College, NewYork-Presbyterian Hospital, 525 E 68th Street, Suite F-838, New York, NY, 10065, USA. Bmf9002@med.cornell.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPopulation-based analyses of 30-day outcomes after parathyroidectomy for renal secondary hyperparathyroidism are limited. We sought to identify risk factors associated with prolonged length of stay (LOS) and readmission in this patient population.

methodsPatients with secondary hyperparathyroidism who underwent parathyroidectomy were reviewed in the ACS-NSQIP database (2011-2016). Patients were identified by ICD codes specific to secondary hyperparathyroidism of renal origin and the ACS-NSQIP variable for current preoperative dialysis. Multivariable logistic regression was used to identify independent factors associated with prolonged LOS and 30-day readmission after parathyroidectomy.

resultsThe cohort included 1846 patients with secondary hyperparathyroidism on dialysis who underwent parathyroidectomy. There were 416 (22.5%) patients classified under the prolonged LOS group. On multivariable analysis, factors associated with prolonged LOS included elevated preoperative alkaline phosphatase [OR 3.13 (95%-CI 2.09-4.70), p < 0.001], decreased preoperative hematocrit [OR 1.83 (95%-CI 1.25-2.68), p = 0.002], unplanned reoperation (OR 5.02 [95%-CI 2.22-11.3], p < 0.001) and any postoperative complication [OR 6.12 (95%-CI 3.31-11.3), p < 0.001]. The overall 30-day readmission rate was 15.0%. Hypocalcemia and hungry bone syndrome accounted for 47.0% (n = 93/198) of readmissions. On multivariable analysis, patients with a history of hypertension and those undergoing unplanned reoperation were at risk of readmission [2.16 (95%-CI 1.21-3.87), p = 0.009, and 2.40 (95%-CI 1.15-5.02), p = 0.020, respectively], whereas reoperative parathyroidectomy was inversely associated with readmission (OR 0.24, 95%-CI 0.07-0.80, p = 0.021).

conclusionIn patients undergoing parathyroidectomy for renal secondary hyperparathyroidism, several readily available preoperative biochemical markers, including those of increased bone turnover and anemia, are associated with prolonged postoperative LOS. Unplanned reoperation was predictive of both increased LOS and readmission.

Indexed as

Patient ReadmissionAdultFemaleHumansHyperparathyroidism, SecondaryLength of StayMaleMiddle AgedParathyroidectomyPostoperative ComplicationsRenal InsufficiencyRetrospective StudiesRisk Factors

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.