Evidence map›Paper›PMID 32737525›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022

Preexisting and treated concomitant ankle instability does not compromise patient-reported outcomes of solitary osteochondral lesions of the talus treated with matrix-induced bone marrow stimulation in the first postoperative year: data from the German Cartilage Registry (KnorpelRegister DGOU).

Marc-Daniel Ahrend, Matthias Aurich, Christoph Becher, Atesch Ateschrang, Steffen Schröter, Markus Walther, Oliver Gottschalk, Christian Plaass, Sarah Ettinger, Wolfgang Zinser and 1 more

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Arthroscopic techniques in ankle surgery.Operative Orthopadie und Traumatologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Marc-Daniel AhrendDepartment of Traumatology and Reconstructive Surgery, BG Trauma Center Tübingen, Eberhard Karls University Tübingen, Schnarrrenbergstr. 95, 72076, Tübingen, Germany. mahrend@bgu-tuebingen.de.ORCID http://orcid.org/0000-0001-7044-4182
Matthias AurichDepartment of Orthopaedics and Special Trauma Surgery, Klinikum Mittleres Erzgebirge gGmbH, Zschopau, Germany.
Christoph BecherInternational Center of Hip-, Knee- and Foot Surgery, Sport Traumatology, ATOS Clinic Heidelberg, Heidelberg, Germany.
Atesch AteschrangDepartment of Traumatology and Reconstructive Surgery, BG Trauma Center Tübingen, Eberhard Karls University Tübingen, Schnarrrenbergstr. 95, 72076, Tübingen, Germany.
Steffen SchröterDepartment of Traumatology and Reconstructive Surgery, Diakonie Klinikum GmbH Jung-Stilling-Krankenhaus, Siegen, Germany.
Markus WaltherSchön Klinik Munich Harlaching - FIFA Medical Centre of Excellence, Munich, Germany.
Oliver GottschalkSchön Klinik Munich Harlaching - FIFA Medical Centre of Excellence, Munich, Germany.
Christian PlaassDepartment for Foot and Ankle surgery, Orthopedic Clinic of the Hannover Medical School in DIAKOVERE Annastift, Anna-von-Borries Strasse 1-7, 30625, Hannover, Germany.
Sarah EttingerDepartment for Foot and Ankle surgery, Orthopedic Clinic of the Hannover Medical School in DIAKOVERE Annastift, Anna-von-Borries Strasse 1-7, 30625, Hannover, Germany.
Wolfgang ZinserDepartment of Orthopaedics and Trauma Surgery, St. Vinzenz Hospital Dinslaken, Dinslaken, Germany.
Daniel KörnerDepartment of Traumatology and Reconstructive Surgery, BG Trauma Center Tübingen, Eberhard Karls University Tübingen, Schnarrrenbergstr. 95, 72076, Tübingen, Germany.
BG Klinik Tübingen · DEMedizinische Hochschule Hannover · DEAO Foundation · CHAtos (France) · FRDiakonie Klinikum Jung-Stilling · DEKlinikum Würzburg Mitte · DELMU Klinikum · DESchön Klinik München Harlaching · DEStadtwerke Dinslaken (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the subjective ankle function within the first year following matrix-induced bone marrow stimulation (M-BMS) of patients with a solitary osteochondral lesion of the talus (OCLT) with and without concomitant chronic ankle instability (CAI).

methodsData from the German Cartilage Registry (KnorpelRegister DGOU) for 78 patients with a solitary OCLT and a follow-up of at least 6 months were included. All patients received M-BMS for OCLT treatment. The cohort was subdivided into patients with OCLT without CAI treated with M-BMS alone (n = 40) and patients with OCLT and CAI treated with M-BMS and additional ankle stabilisation (n = 38). The Foot and Ankle Ability Measure (FAAM), the Foot and Ankle Outcome Score (FAOS), and the Numeric Rating Scale for Pain (NRS) were used to assess patient-reported outcomes (median (minimum-maximum)).

resultsFrom preoperatively to 12 months postoperatively, patients with OCLT without CAI treated with M-BMS alone had a significant improvement of all subscales in the FAAM [activity of daily living 64.3 (10-100) to 88.1 (39-100); sports 34.4 (0-100) to 65.6 (13-94), functional activities of daily life 50 (0-90) to 80 (30-100), functional sports 30 (0-100) to 70 (5-100)] and FAOS [pain 61.1 (8-94) to 86.1 (50-100), symptoms 60.7 (18-96) to 76.8 (29-100), activities of daily living 72.1 (24-100) to 91.9 (68-100), sport/recreational activities 30.0 (0-70) to 62.5 (0-95), quality of life 31.3 (6-50) to 46.9 (19-100)]. Within the first year, patients with OCLT and CAI treated with M-BMS and ankle stabilisation also showed significant improvement in the FAAM [activity of daily living 68.8 (5-99) to 90.5 (45-100); sports 32.8 (0-87.5) to 64.1 (0-94), functional activities of daily life 62.5 (25-100) to 80 (60-90), functional sports 30 (0-100) to 67.5 (0.95)] and the FAOS [pain 66.7 (28-92) to 87.5 (47-100), symptoms 57.1 (29-96) to 78.6 (50-100), activities of daily living 80.1 (25-100) to 98.5 (59-100), sport/recreational activities 35.0 (0-100) to 70.0 (0-100), quality of life 25.0 (0-75) to 50.0 (19-94)]. The pain level decreased significantly in both groups. No significant difference was found between both groups regarding the subscales of FAAM, FAOS and the NRS 1 year postoperatively.

conclusionImprovements in subjective ankle function, daily life activities and sports activities were observed within the first year following M-BMS. Our results suggest that preexisting and treated ankle instability did not compromise subjective outcome in patients treated with M-BMS in the first postoperative year. LEVEL OF EVIDENCE: Level IV.

Indexed as

Cartilage, ArticularIntra-Articular FracturesJoint InstabilityTalusActivities of Daily LivingAnkleBone MarrowHumansPainPatient Reported Outcome MeasuresQuality of LifeRegistriesTreatment OutcomeAnkleAnkle instabilityCartilageCartilage registryKnorpelregisterOsteochondral lesionTalus

Identifiers

PMID32737525
OpenAlexW3045498577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.