Evidence map›Paper›PMID 32737159›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Lysosomal activity regulates

Wei Wei, Gary Ruvkun

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

  1. Vitamin BNature communications · 2026
    Article
  2. Raptor and Drp1 Function Synthetically to Control Hypoxic Death and the Mitochondrial Network in Caenorhabditis elegans.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Vitamin BResearch square · 2025
    Article
  10. Article
  11. A critical role forActa pharmaceutica Sinica. B · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Mitochondrial recovery by the UPRSeminars in cell & developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wei WeiDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.ORCID 0000-0002-8699-8742
Gary RuvkunDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114; ruvkun@molbio.mgh.harvard.edu.
Harvard University · US

Funding

GENETIC AND MOLECULAR BASIS OF LONGEVITYR01AG016636 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI GARY B RUVKUN · 1999 to 2026
$12.4M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIA NIH HHS R01 AG016636NIH HHS P40 OD010440
6 · The paper itself

Abstract

Mitochondrial fission and fusion are highly regulated by energy demand and physiological conditions to control the production, activity, and movement of these organelles. Mitochondria are arrayed in a periodic pattern in

Indexed as

5-Methyltetrahydrofolate-Homocysteine S-MethyltransferaseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDynaminsLysosomesMitochondriaMitochondrial DynamicsMutationVitamin B 125-Methyltetrahydrofolate-Homocysteine S-MethyltransferaseCaenorhabditis elegans Proteinsdynamin-related protein 1, C elegansDynaminsVitamin B 12interorganelle communicationmethionine restrictionmitochondrial dynamicsvacuolar V-ATPasevitamin B12

Identifiers

PMID32737159
PMCPMC7443905
OpenAlexW3046665718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.