Evidence map›Paper›PMID 32737150›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.

Akimichi Inaba, Zewen K Tuong, Alexandra M Riding, Rebeccah J Mathews, Jack L Martin, Kourosh Saeb-Parsy, Menna R Clatworthy

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 38 citations in OpenAlex.

  1. Observational
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  15. Monocytes and Macrophages in Kidney Disease and Homeostasis.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Pleural macrophages translocate to the lung during infection to promote improved influenza outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
  20. miR-181c, a potential mediator for acute kidney injury in a burn rat model with following sepsis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Akimichi InabaMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom; mrc38@cam.ac.uk.ORCID 0000-0002-9726-9860
Zewen K TuongMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom.
Alexandra M RidingMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom.ORCID 0000-0002-6915-5671
Rebeccah J MathewsMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom.ORCID 0000-0002-3834-4744
Jack L MartinCambridge University Hospitals National Health Service Foundation Trust, Cambridge CB2 0QQ, United Kingdom.ORCID 0000-0001-9545-0298
Kourosh Saeb-ParsyDepartment of Surgery, University of Cambridge, Cambridge CB2 0QQ, United Kingdom; and.ORCID 0000-0002-0633-3696
Menna R ClatworthyMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom.ORCID 0000-0002-3340-9828
MRC Laboratory of Molecular Biology · GBNational Health Service · GBUniversity of Cambridge · GB

Funding

Department of Health RP-2017-08-ST2-002Medical Research Council MR/M003868/1Medical Research Council MR/N024907/1Medical Research Council MR/S035842/1Versus Arthritis 21777Wellcome TrustWellcome Trust 200110/Z/15/Z
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a serious condition affecting one fifth of hospital inpatients. B lymphocytes have immunological functions beyond Ab production and may produce cytokines and chemokines that modulate inflammation. In this study, we investigated leukocyte responses in a mouse model of AKI and observed an increase in circulating and kidney B cells, particularly a B220

Indexed as

Acute Kidney InjuryAnimalsB-LymphocytesChemokine CCL7CytokinesDisease Models, AnimalFemaleHumansInflammationKidneyLeukocytesMaleMiceMice, Inbred BALB CMice, Inbred C57BLMonocytesCcl7 protein, mouseChemokine CCL7Cytokines

Identifiers

PMID32737150
PMCPMC7444279
OpenAlexW3046508727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.