Evidence map›Paper›PMID 32737145›Full record

ArticleThe Journal of biological chemistry2020

The adaptor protein SHCA launches cancer invasion.

Supriya Borah, Neil A Bhowmick

Open access · hybridAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Supriya BorahDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Neil A BhowmickDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA bhowmickn@cshs.org.ORCID 0000-0001-8747-5989
Cedars-Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cell invasion and metastasis rely on invadopodia, important extensions of the cytoskeleton that initiate degradation of the basement membrane that holds a cell in place. Transforming growth factor-β (TGF-β) is well-known to induce breast cancer migration and invasion, but the mechanism by which TGF-β signaling converts into cell motility is not completely understood. A study from Kiepas

Indexed as

Breast NeoplasmsLipomaPodosomesAdaptor Proteins, Signal TransducingCell MovementCollagenHumansSrc Homology 2 Domain-Containing, Transforming Protein 1Transforming Growth Factor betaAdaptor Proteins, Signal TransducingCollagenSrc Homology 2 Domain-Containing, Transforming Protein 1Transforming Growth Factor beta

Identifiers

PMID32737145
PMCPMC7397101
OpenAlexW3046655523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.