Evidence map›Paper›PMID 32736647›Full record

ArticleJournal of ovarian research2020

Follicular phase length has no influence on frozen-thawed embryo transfers in natural cycles.

Ying Ying, Fuman Qiu, Qing Huang, Sichen Li, Haiying Liu, Jianqiao Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of ovarian research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ying YingReproductive Medicine Center, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, China.
Fuman QiuThe State Key Lab of Respiratory Disease, Collaborative Innovation Center for Environmental Toxicity, The School of Public Health, Guangzhou Medical University, Guangzhou, China.
Qing HuangReproductive Medicine Center, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, China.
Sichen LiReproductive Medicine Center, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, China.
Haiying LiuReproductive Medicine Center, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, China. liuhaiying0606@163.com.
Jianqiao LiuReproductive Medicine Center, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, China. liujqssz@gzhmu.edu.cn.
Third Affiliated Hospital of Guangzhou Medical University · CNGuangzhou Medical University · CN

Funding

Young Scientists Fund grant numbers 81701518
6 · The paper itself

Abstract

backgroundWhether menstrual variability in women with regular and ovulatory cycle could affect embryo implantation remains controversial, with conflicting evidences presented in the literature. Thus, in this study, we evaluated the impact of prolonged follicular phase length (FPL) on the clinical pregnancy rate (CPR) after frozen-thawed embryo transfer (FET) in true natural cycles (NC).

methodsThis retrospective cohort study utilized data from a large university-affiliated reproductive medicine center. Women undergoing true NC-FET were grouped as per their FPL type: Prolonged FPL (n = 127) and Normal FPL (n = 737). The primary study outcome was CPR in these 2 groups.

resultsThe FPL in the current cycle was significantly longer in the Prolonged FPL group (23.0 ± 2.4) than in the Normal FPL group (16.0 ± 2.2; p < 0.001). The crude CPR was significantly higher in the Prolonged FPL group (61.4%) than in the Normal FPL group (51.7%; p = 0.043). After adjusting for the results of potential confounders including the age, BMI, percent of optimal embryos transferred, and endometrial thickness, the difference in the CRP between the 2 groups disappeared (OR 1.28, 95% CI: 0.86-1.91, p = 0.232). No statistically significant difference was noted in the rates of implantation and miscarriage.

conclusionsThe current FET should not be cancelled if the ovulation time exceeds the predicted period based on the length of the previous menstrual cycle in the light of no negative effect on the pregnancy outcome.

Indexed as

Pregnancy RateAdultBody Mass IndexCase-Control StudiesCryopreservationEmbryo ImplantationEmbryo TransferFemaleFollicular PhaseHumansMaternal AgePregnancyRetrospective StudiesYoung AdultFollicular phase lengthFrozen–thawed embryo transferNatural cycle

Identifiers

PMID32736647
PMCPMC7393903
OpenAlexW3046394377

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.