Evidence map›Paper›PMID 32735213›Full record

ArticleeLife2020

Gap junctions deliver malonyl-CoA from soma to germline to support embryogenesis in

Todd A Starich, Xiaofei Bai, David Greenstein

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  11. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. TheeLife · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Journal of developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Todd A StarichDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.
Xiaofei BaiNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, United States.ORCID 0000-0001-8179-8162
David GreensteinDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.ORCID 0000-0001-8189-2087
University of Minnesota · USNational Institutes of Health · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
CONTROL OF MEIOSIS AND GERMLINE PROLIFERATIONR01GM057173 · NIGMS · VANDERBILT UNIVERSITY · PI GREENSTEIN, DAVID IRWIN · 1998 to 2021
$6.6M
Control of Meiosis and Germline ProliferationR56GM057173 · NIGMS · UNIVERSITY OF MINNESOTA · PI GREENSTEIN, DAVID IRWIN · 2008 to 2008
$310k
NIGMS NIH HHS R01 GM057173NIGMS NIH HHS R56 GM057173NIH HHS P40 OD010440
6 · The paper itself

Abstract

Gap junctions are ubiquitous in metazoans and play critical roles in important biological processes, including electrical conduction and development. Yet, only a few defined molecules passing through gap junction channels have been linked to specific functions. We isolated gap junction channel mutants that reduce coupling between the soma and germ cells in the

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryonic DevelopmentEmbryo, NonmammalianGap JunctionsGerm CellsGonadsMalonyl Coenzyme ACaenorhabditis elegans ProteinsMalonyl Coenzyme AC. elegansdevelopmental biologygap junctionsgeneticsgenomicsgermline developmentsoma-germline interactions

Identifiers

PMID32735213
PMCPMC7445009
OpenAlexW3046341834

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.