Evidence map›Paper›PMID 32735090›Full record

ArticleJournal of veterinary science2020

Serum homocysteine concentration in dogs with immunosuppressant-responsive enteropathy.

Elena Benvenuti, Alessio Pierini, Eleonora Gori, Enrico Bottero, Marco Pietra, Ilaria Lippi, Valentina Meucci, Veronica Marchetti

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elena BenvenutiDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy.ORCID https://orcid.org/0000-0001-5462-348X
Alessio PieriniDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy. pierini.alessio2004@libero.it.ORCID https://orcid.org/0000-0002-9336-5150
Eleonora GoriDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy.ORCID https://orcid.org/0000-0001-8612-5573
Enrico BotteroEndovet Italia, 00100 Rome, Italy.
Marco PietraDepartment of Veterinary Clinical Sciences, University of Bologna, 40064 Bologna, Italy.ORCID https://orcid.org/0000-0003-4431-0791
Ilaria LippiDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy.ORCID https://orcid.org/0000-0002-3595-6067
Valentina MeucciDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy.ORCID https://orcid.org/0000-0001-5672-7856
Veronica MarchettiDepartment of Veterinary Science, University of Pisa, 56122 Pisa, Italy.ORCID https://orcid.org/0000-0001-6099-6223
University of Pisa · ITEndometriosis · GBUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHomocysteine (HCY) was evaluated in healthy and chronic enteropathic dogs, however no studies on dogs with immunosuppressant-responsive enteropathy are available.

objectivesThe aim was to evaluate serum HCY concentrations and its prognostic role in dogs with immunosuppressant-responsive enteropathy compared to healthy dogs.

methodsSerum HCY concentration was statistically compared between 24 healthy dogs and 29 dogs with immunosuppressant-responsive enteropathy. Correlation analyses between serum total protein, albumin (ALB), C-reactive protein (CRP), folate and cobalamin, and serum HCY concentration were performed in immunosuppressant-responsive enteropathic dogs.

resultsThe associations between serum HCY concentration and clinical, histological, endoscopic scores and follow-up were evaluated. Mean serum HCY concentration was higher in immunosuppressant-responsive enteropathic dogs compared to control dogs (30.22 ± 8.67 μmol/L vs. 5.26 ± 2.78 μmol/L;

conclusionsAlthough, serum HCY concentration was higher in immunosuppressant-responsive enteropathy, its prognostic value remains unclear. However, further prospective, large-scale studies are warranted to better investigate the possible prognostic role of HCY in immunosuppressant-responsive enteropathic dogs.

Indexed as

AnimalsDog DiseasesDogsEnteritisFemaleHomocysteineImmunosuppressive AgentsMalePrognosisHomocysteineImmunosuppressive AgentscanineCCECAICobalaminfolateHPLC

Identifiers

PMID32735090
PMCPMC7402937
OpenAlexW3022196065

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.