SynthesisClinical cardiology2020
N-terminal pro-brain natriuretic peptide and short-term mortality in acute aortic dissection: A meta-analysis.
Synthesis in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- ADMISSION CARDIAC TROPONINS PREDICT HOSPITAL MORTALITY IN TYPE A ACUTE AORTIC DISSECTION: A META-ANALYSIS OF ADJUSTED RISK ESTIMATES.Acta clinica Croatica · 2021Pooled it
- N-terminal pro-brain natriuretic peptide and short-term mortality in acute aortic dissection: A meta-analysis.Clinical cardiology · 2020Pooled it
- Predictive Value of D-Dimer to Albumin Ratio for Outcome in Acute Type A Aortic Dissection Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Centroid Regression for Preoperative Risk Assessment of Acute Type A Aortic Dissection Based on Multivariate Clinical Data.Journal of clinical medicine · 2026Article
- CHA2DS2-VA Score Can Be Used to Predict In-Hospital Mortality in Patients with Acute Aortic Dissection.Brazilian journal of cardiovascular surgery · 2026Article
- Admission blood pressure and mortality in acute aortic dissection: Southwest China multicenter retrospective cohort study.Scientific reports · 2026Article
- Circulating Plasma Proteins Influence the Risk of Aortic Dissection via Blood Pressure: A Network Mendelian Randomization and Multi-Omics Study.Journal of inflammation research · 2026Article
- Prognostic value of cardiac biomarkers in surgery for acute type A aortic dissection: mid-term follow-up results.Journal of thoracic disease · 2025Article
- An acute aortic dissection prognostic score for predicting early in-hospital mortality in acute thoracic aortic dissection.American heart journal plus : cardiology research and practice · 2025Article
- Clinical implication of NT-proBNP to predict mortality in patients with acute type A aortic dissection: a retrospective cohort study.BMJ open · 2025Article
- Association Between Lactate Dehydrogenase/Albumin Ratio and in-Hospital Mortality in Patients with Acute Aortic Dissection.Journal of inflammation research · 2025Article
- Atypical presentation of DeBakey type I aortic dissection mimicking pulmonary embolism in a pregnant patient: a case report.Journal of Yeungnam medical science · 2024Article
- Predictive value of admission COScientific reports · 2023Article
- Changes of Serum D-Dimer, NT-proBNP, and Troponin I Levels in Patients with Acute Aortic Dissection and the Clinical Significance.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- S100A1 as a potential biomarker for the diagnosis of patients with acute aortic dissection.The Journal of international medical research · 2021Article
- Risk Factors for Postoperative Mortality in Patients with Acute Stanford Type A Aortic Dissection.International journal of general medicine · 2021Article
- Lysophosphatidic Acid May Be a Novel Biomarker for Early Acute Aortic Dissection.Frontiers in surgery · 2021Article
- Association Between the Admission Serum Bicarbonate and Short-Term and Long-Term Mortality in Acute Aortic Dissection Patients Admitted to the Intensive Care Unit.International journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute aortic dissection (AAD) is a life-threatening medical emergency that requires immediate diagnosis and rapid treatment. There is a paucity of data on the role of biomarkers in risk stratification of patients with AAD. HYPOTHESIS: N-terminal pro-brain natriuretic peptide (NT-proBNP) is associated with short-term mortality in AAD patients.
methodsWe systematically searched Medline and Scopus to identify all observational cohort studies published before January 2020 that compared outcome (short-term mortality) in patients with AAD with high vs low levels of baseline NT-proBNP combining terms "brain natriuretic peptide" and "aortic dissection." A meta-analysis was conducted using the generic inverse variance method. Heterogeneity between studies was investigated using the Cochrane's Q test and I
resultsFour studies were included in final analysis including a total of 950 patients, and 105 (11%) patients died. Baseline NT-proBNP concentrations were significantly higher in nonsurvivors (median 2240 pg/mL, range 1678-16 347 pg/mL) when compared to survivors (665 pg/mL, 328-1252 pg/mL). Elevated NT-proBNP values were significantly associated with an increased risk of short-term mortality (odds ratio 4.13, 95% CI [confidence interval] 2.33-7.33), with low heterogeneity (I
conclusionElevated NT-proBNP levels on admission are associated with an increased risk of short-term mortality in AAD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.