Evidence map›Paper›PMID 32734805›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Implementing Rapid Initiation of Antiretroviral Therapy for Acute HIV Infection Within a Routine Testing and Linkage to Care Program in Chicago.

Moira McNulty, Jessica Schmitt, Eleanor Friedman, Bijou Hunt, Audra Tobin, Anjana Bairavi Maheswaran, Janet Lin, Richard Novak, Beverly Sha, Norma Rolfsen and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Moira McNultySection of Infectious Diseases and Global Health, University of Chicago, IL, USA.ORCID 0000-0002-9651-254X
Jessica SchmittSection of Infectious Diseases and Global Health, University of Chicago, IL, USA.
Eleanor FriedmanSection of Infectious Diseases and Global Health, University of Chicago, IL, USA.
Bijou HuntSinai Infectious Disease Center, Sinai Health System, Chicago, IL, USA.
Audra TobinSinai Infectious Disease Center, Sinai Health System, Chicago, IL, USA.
Anjana Bairavi MaheswaranUniversity of Illinois Hospital and Health Sciences and Systems, Chicago, IL, USA.
Janet LinUniversity of Illinois Hospital and Health Sciences and Systems, Chicago, IL, USA.
Richard NovakUniversity of Illinois Hospital and Health Sciences and Systems, Chicago, IL, USA.
Beverly ShaDivision of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA.
Norma RolfsenMercy Hospital and Medical Center, Chicago, IL, USA.
Arthur MoswinMercy Hospital and Medical Center, Chicago, IL, USA.
Breon RoseFriend Health Center, Chicago, IL, USA.
David PitrakSection of Infectious Diseases and Global Health, University of Chicago, IL, USA.
Nancy GlickSinai Infectious Disease Center, Sinai Health System, Chicago, IL, USA.
University of Chicago · USSinai Health System · USUniversity of Illinois Chicago · USMercy Hospital and Medical Center · USRush University Medical Center · US

Funding

Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael E Newcomb · 2015 to 2026
$38.4M
Northwestern University Clinical Trial UnitU01AI069471 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MURPHY, ROBERT LEO · 2007 to 2011
$12.0M
INNOVATIVE IMPLEMENTATION RESEARCH METHODS COREP30DA027828 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BROWN, C. HENDRICKS, MUSTANSKI, BRIAN · 2011 to 2020
$11.4M
Implementation Science to Strengthen the Integrated Care Continuum in Getting to Zero ContextsK23MH118969 · NIMH · UNIVERSITY OF CHICAGO · PI MCNULTY, MOIRA · 2019 to 2022
$682k
NIAID NIH HHS P30 AI117943NIAID NIH HHS U01 AI069471NIDA NIH HHS P30 DA027828NIMH NIH HHS K23 MH118969
6 · The paper itself

Abstract

Growing evidence suggests that rapid initiation of antiretroviral therapy for HIV improves care continuum outcomes. We evaluated process and clinical outcomes for rapid initiation in acute HIV infection within a multisite health care-based HIV testing and linkage to care program in Chicago. Through retrospective analysis of HIV testing data (2016-2017), we assessed linkage to care, initiation of antiretroviral therapy, and viral suppression. Of 334 new HIV diagnoses, 33 (9.9%) individuals had acute HIV infection. Median time to linkage was 11 (interquartile range [IQR]: 5-19.5) days, with 15 days (IQR 5-27) to initiation of antiretroviral therapy. Clients achieved viral suppression at a median of 131 (IQR: 54-188) days. Of all, 69.7% were retained in care, all of whom were virally suppressed. Sites required few additional resources to incorporate rapid initiation into existing processes. Integration of rapid initiation of antiretroviral therapy into existing HIV screening programs is a promising strategy for scaling up this important intervention.

Indexed as

Health Plan ImplementationMass ScreeningAcute DiseaseAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountChicagoContinuity of Patient CareFemaleHIV InfectionsHumansMaleMiddle AgedRetrospective StudiesYoung AdultAnti-HIV Agentsacute HIV infectionantiretroviral treatmentcontinuum of careHIVHIV testinglinkage to care

Identifiers

PMID32734805
PMCPMC7401059
OpenAlexW3046344091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.