Evidence map›Paper›PMID 32734734›Full record

ArticleYonsei medical journal2020

Survival Trend of HIV/AIDS Patients Starting Antiretroviral Therapy in South Korea between 2001 and 2015.

Yong Chan Kim, Jin Young Ahn, Hyo Youl Kim, Joon Young Song, Dae Won Park, Min Ja Kim, Hee Jung Choi, Shin Woo Kim, Mee Kyung Kee, Myung Guk Han and 6 more

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Yong Chan KimDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5081-7906
Jin Young AhnDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3740-2826
Hyo Youl KimDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-7827-902X
Joon Young SongDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0148-7194
Dae Won ParkDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7653-686X
Min Ja KimDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2125-7521
Hee Jung ChoiDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1468-4074
Shin Woo KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-3755-8249
Mee Kyung KeeDivision of Viral Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Korea.ORCID https://orcid.org/0000-0001-7361-8811
Myung Guk HanDivision of Viral Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Korea.ORCID https://orcid.org/0000-0002-3543-1826
Myeongsu YooDivision of Viral Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Korea.ORCID https://orcid.org/0000-0001-8542-8898
Soo Min KimInstitute for Health and Society, Hanyang University, Seoul, Korea.ORCID https://orcid.org/0000-0002-6822-9050
Yunsu ChoiInstitute for Health and Society, Hanyang University, Seoul, Korea.ORCID https://orcid.org/0000-0001-7682-7993
Bo Youl ChoiDepartment of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0115-5736
Sang Il KimDivision of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-9361-7381
Jun Yong ChoiDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2775-3315
Yonsei University · KRKorea National Institute of Health · KRKorea University · KRKyungpook National University · KRHanyang University · KREwha Womans University · KR

Funding

Korea Centers for Disease Control & Prevention 2019-E5103-00Korea Centers for Disease Control & Prevention 4800-4859-304
6 · The paper itself

Abstract

purposeIn the recent antiretroviral therapy (ART) era, a large proportion of Korean patients with human immunodeficiency virus (HIV) infection were shown to have low CD4 cell counts at diagnosis and during ART initiation. We investigated the survival trends in patients living with HIV/acquired immunodeficiency syndrome (AIDS) in Korea who started ART in the 2000s, and evaluated the risk factors for mortality to elucidate the association between survival and low CD4 cell counts at ART initiation. MATERIALS AND

methodsPatients with HIV infection who were aged >18 years and had started ART between 2001 and 2015 in the Korean HIV/AIDS cohort study were enrolled. We compared the clinical characteristics, mortality, and causes of death among the enrolled subjects based on the time of ART initiation. Cox regression analysis was used to estimate the adjusted hazard ratios of mortality based on the time of ART initiation.

resultsAmong the 2474 patients enrolled, 105 (4.24%) died during the follow-up period of 9568 patient-years. Although CD4 cell counts at the time of ART initiation significantly increased from 161 [interquartile range (IQR), 73.5-303] in 2001-2003 to 273 (IQR, 108-399) in 2013-2015 (

conclusionDespite excellent HIV care available in the recent ART era, the survival of patients with HIV/AIDS undergoing ART did not improve between 2001 and 2015 in Korea.

Indexed as

Antiretroviral Therapy, Highly ActiveAcquired Immunodeficiency SyndromeAdultCause of DeathCD4 Lymphocyte CountCohort StudiesFemaleHumansMaleMiddle AgedProportional Hazards ModelsRepublic of KoreaRisk FactorsSurvival AnalysisAnti-retroviral agentsHIVRepublic of Koreasurvival

Identifiers

PMID32734734
PMCPMC7393295
OpenAlexW3045761595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.