Evidence map›Paper›PMID 32734733›Full record

ArticleYonsei medical journal2020

Identification of Fungal Species and Detection of Azole-Resistance Mutations in the

In Young Jung, Youn Jung Lee, Hyo Sup Shim, Yun Suk Cho, Yu Jin Sohn, Jong Hoon Hyun, Yae Jee Baek, Moo Hyun Kim, Jung Ho Kim, Jin Young Ahn and 7 more

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Molecular and Phenotypic Characterization of Multidrug-ResistantJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

In Young JungDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-2680-5224
Youn Jung LeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2490-2485
Hyo Sup ShimDepartment of Pathology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5718-3624
Yun Suk ChoDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6089-876X
Yu Jin SohnDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7018-8641
Jong Hoon HyunDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9621-0250
Yae Jee BaekDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0994-4940
Moo Hyun KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3634-0296
Jung Ho KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5033-3482
Jin Young AhnDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3740-2826
Su Jin JeongDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4025-4542
Nam Su KuDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9717-4327
Yoon Soo ParkDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4640-9525
Joon Sup YeomDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8940-7170
Young Keun KimDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-2120-6265
Hyo Youl KimDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-7827-902X
Jun Yong ChoiDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2775-3315
Yonsei University · KR

Funding

Korea Centers for Disease Control and Prevention 2019-ER5408-00Korea HIV/AIDS Cohort Study 2019-ER5101-00Ministry of Health and Welfare HI14C1324
6 · The paper itself

Abstract

purposeWith changing fungal epidemiology and azole resistance in MATERIALS AND

methodsA total of 75 FFPE specimens with a histopathological diagnosis of aspergillosis or mucormycosis were identified during the 10-year study period (2006-2015). After deparaffinization and DNA extraction, panfungal PCR assays were conducted on FFPE samples for fungal species identification. The identified fungal species were compared with histopathological diagnosis. On samples identified as

resultsSpecific fungal DNA was identified in 31 (41.3%) FFPE samples, and of these, 16 samples of specific fungal DNA were in accord with a histopathological diagnosis of aspergillosis or mucormycosis; 15 samples had discordant histopathology and PCR results. No azole-mediating

conclusionPanfungal PCR assay with FFPE samples may provide additional information of use to fungal species identification. No azole-resistance mediating mutations in the

Indexed as

HospitalsAgedAged, 80 and overAspergillus fumigatusAzolesCytochrome P-450 Enzyme SystemDrug Resistance, FungalFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMutationRepublic of KoreaAzolesCytochrome P-450 Enzyme SystemAspergillosisfungusmucormycosispolymerase chain reactionresistance

Identifiers

PMID32734733
PMCPMC7393294
OpenAlexW3045813032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.