Evidence map›Paper›PMID 32734732›Full record

Trial reportYonsei medical journal2020

Effects of Air Purifiers on Patients with Allergic Rhinitis: a Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study.

Kyung Hee Park, Da Woon Sim, Sang Chul Lee, Sunyoung Moon, Eunju Choe, Hyejung Shin, Sung Ryeol Kim, Jae Hyun Lee, Hyung Ho Park, Deok Huh and 1 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026
    Review
  3. Article
  4. Targeting Pollutants in the Treatment and Prevention of Atopic Dermatitis.Immunology and allergy clinics of North America · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. KAAACI Guidelines for Allergen Immunotherapy.Allergy, asthma & immunology research · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Kyung Hee ParkDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3605-5364
Da Woon SimDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9723-0720
Sang Chul LeeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5318-6804
Sunyoung MoonAir Care Advanced R&D, Home Appliance & Air Solution Company, LG Electronics, Seoul, Korea.ORCID https://orcid.org/0000-0002-3765-197X
Eunju ChoeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0012-472X
Hyejung ShinBiostatistics Collaboration Unit, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5346-7278
Sung Ryeol KimDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7418-0049
Jae Hyun LeeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0760-0071
Hyung Ho ParkAir Care Advanced R&D, Home Appliance & Air Solution Company, LG Electronics, Seoul, Korea.ORCID https://orcid.org/0000-0002-4768-4150
Deok HuhAir Care Advanced R&D, Home Appliance & Air Solution Company, LG Electronics, Seoul, Korea.ORCID https://orcid.org/0000-0001-7675-1044
Jung Won ParkDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0249-8749
Yonsei University · KRLG (United States) · USChonnam National University · KR

Funding

LG Electronics
6 · The paper itself

Abstract

purposeExposure to particulate matter (PM) is a well-known risk factor in the triggering and exacerbation of allergic airway disease. Indoor environments, where people spend most of their time, are of utmost importance. To assess the effects of air purifiers [equipped with high-efficiency particulate air (HEPA) filters] on allergic rhinitis (AR) in adult patients, we performed a multicenter, randomized, double-blind, and placebo-controlled study. MATERIALS AND

methodsPatients with house dust mite (HDM)-induced AR were randomly assigned to either active or mockup (placebo) air-purification groups. Two air purifiers (placed in living room and bedroom) were operated for 6 weeks in each home environment. The primary study endpoint was to achieve improvement in AR symptoms and medication scores. Secondary endpoints were to achieve improvement in the quality of life (QoL) and visual analog scale (VAS) scores, as well as in the indoor (bedroom and living room) concentrations of PM

resultsAfter 6 weeks of air purifier use, medication scores improved significantly in the active (vs. placebo) group, although subjective measures (symptoms, VAS, and QoL scores) did not differ. Bedroom PM

conclusionThe use of air purifiers with HEPA filters significantly reduced medication requirements for patients with HDM-induced AR and significantly lowered indoor PM

Indexed as

Air FiltersAdultAir PollutantsAir Pollution, IndoorDouble-Blind MethodFemaleHumansMaleParticulate MatterPlacebosQuality of LifeRhinitis, AllergicRisk FactorsTime FactorsAir PollutantsParticulate MatterPlacebosAir purifierallergic rhinitishouse dust miteindoor pollutionparticulate matter

Identifiers

PMID32734732
PMCPMC7393300
OpenAlexW3046042121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.