Evidence map›Paper›PMID 32734528›Full record

ArticlePediatric cardiology2020

Prophylactic Peritoneal Drainage is Associated with Improved Fluid Output after Congenital Heart Surgery.

Kevin A Pettit, Nicholas A Schreiter, Entela B Lushaj, Joshua L Hermsen, Michael Wilhelm, Allison C Redpath Mahon, Kari L Nelson, Joshua J DeGrave, Nicholas Marka, Petros V Anagnostopoulos

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kevin A PettitDepartment of Pediatrics, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Nicholas A SchreiterSchool of Medicine and Public Health, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Entela B LushajDivision of Cardiothoracic Surgery, Department of Surgery, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Joshua L HermsenDivision of Cardiothoracic Surgery, Department of Surgery, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Michael WilhelmDepartment of Pediatrics, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Allison C Redpath MahonDepartment of Pediatrics, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Kari L NelsonDivision of Cardiothoracic Surgery, Department of Surgery, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Joshua J DeGraveSchool of Pharmacy, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Nicholas MarkaDivision of Cardiothoracic Surgery, Department of Surgery, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA.
Petros V AnagnostopoulosDivision of Cardiothoracic Surgery, Department of Surgery, The American Family Children's Hospital, University of Wisconsin Hospital and Clinics, 1675 Highland Ave, Madison, WI, 53792, USA. petros@surgery.wisc.edu.ORCID http://orcid.org/0000-0003-0976-8270
UW Health University Hospital · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infants undergoing congenital heart surgery (CHS) with cardiopulmonary bypass (CPB) are at risk of acute kidney injury (AKI) and fluid overload. We hypothesized that placement of a passive peritoneal drain (PPD) can improve postoperative fluid output in such infants. We analyzed 115 consecutive patients, age birth to 60 days, admitted to the PICU after CHS with CPB between 2012 and 2018. Patients who needed postoperative ECMO were excluded. Linear and logistic regression models compared postoperative fluid balances, diuretics administration, AKI, vasoactive-inotropic scores (VIS), time intubated, and length of stay after adjusting for pre/operative predictors including STAT category, bypass time, age, weight, and open chest status. PPD patients had higher STAT category (p = 0.001), longer CPB times (p = 0.001), and higher VIS on POD 1-3 (p ≤ 0.005 daily). PPD patients also had higher AKI rates (p = 0.01) that did not reach significance in multivariable modeling. There were no postoperative deaths. Postoperative hours of intubation, hospital length of stay, and POD 1-5 fluid intake did not differ between groups. Over POD 1-5, PPD use accounted for 48.8 mL/kg increased fluid output (95% CI [2.2, 95.4], p = 0.043) and 3.41 mg/kg less furosemide administered (95% CI [1.69, 5.14], p < 0.001). No PPD complications were observed. Although PPD placement did not affect end-outcomes, it was used in higher acuity patients. PPD placement is associated with improved fluid output despite lower diuretic administration and may be a useful postoperative fluid management adjunct in some complex CHS patients.

Indexed as

Peritoneal CavityAcute Kidney InjuryCardiopulmonary BypassDiureticsDrainageFemaleFurosemideHeart Defects, CongenitalHumansInfantInfant, NewbornLength of StayLogistic ModelsMalePostoperative ComplicationsPostoperative PeriodDiureticsFurosemideCongenital heart surgeryNeonatePerioperative carePostoperative care

Identifiers

PMID32734528
PMCPMC7391225
OpenAlexW3046854225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.