Evidence map›Paper›PMID 32734525›Full record

ArticleMagma (New York, N.Y.)2021

Diffusion-weighted imaging in the assessment of renal function in patients with diabetes mellitus type 2.

Tijana Mrđanin, Olivera Nikolić, Una Molnar, Milena Mitrović, Viktor Till

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In one paragraph

Article in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tijana MrđaninCentre of Radiology, Clinical Centre of Vojvodina, Hajduk Veljkova 1-9, 21000, Novi Sad, Serbia. tmrdjanin@gmail.com.
Olivera NikolićCentre of Radiology, Clinical Centre of Vojvodina, Hajduk Veljkova 1-9, 21000, Novi Sad, Serbia.
Una MolnarCentre of Radiology, Clinical Centre of Vojvodina, Hajduk Veljkova 1-9, 21000, Novi Sad, Serbia.ORCID http://orcid.org/0000-0001-9003-915X
Milena MitrovićFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Viktor TillCentre of Radiology, Clinical Centre of Vojvodina, Hajduk Veljkova 1-9, 21000, Novi Sad, Serbia.
University of Novi Sad · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInvestigation of functional magnetic resonance (MR) imaging role in early diagnosis of diabetic nephropathy (DN) in patients with diabetes mellitus (DM) type 2, by quantification of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values. MATERIAL AND

methods10 healthy volunteers and 91 DM type 2 patients were scanned using diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) sequences. Patients were divided into four groups based on the estimated glomerular filtration value (eGFR). ADC and FA values, calculated in six regions of interest in each kidney (cortex and medulla), were compared to eGFR and laboratory parameters of renal function.

resultsADC values of DM patients were higher in the cortex than in the medulla (p < 0.01), while FA values were higher in the medulla (p = 0.284). Creatinine, cystatin C negatively correlated with ADC (cortex, medulla, parenchyma). Medullary FA were lower in DM patients and positively correlated with the eGFR (p = 0.049). Tractography showed disturbed structure in patients with impaired renal function. DISCUSSION: Medullary FA value is a more sensitive parameter than parenchymal ADC in the early detection of renal damage in DM patients. ADC and FA values are significant in the diagnosis of DN; further research is needed for the update and refinement of the established recommendations.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAnisotropyDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingGlomerular Filtration RateHumansDiabetes mellitus type 2Diabetic nephropathiesDiffusion magnetic resonance imagingDiffusion tensor imaging

Identifiers

PMID32734525
OpenAlexW3046663615

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.