Evidence map›Paper›PMID 32734518›Full record

ReviewDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2020

Classification of the present pharmaceutical agents based on the possible effective mechanism on the COVID-19 infection.

Maryam Amini Pouya, Seyyedeh Maryam Afshani, Armin Salek Maghsoudi, Shokoufeh Hassani, Kayvan Mirnia

Open access · bronzeAbstract readReview
In one paragraph

Review in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Increased ACE2, sRAGE, and Immune Activation, but Lowered Calcium and Magnesium in COVID-19.Recent advances in inflammation & allergy drug discovery · 2022
    Article
  5. Rlip Protein: A Potential Target for COVID-19.Journal of community hospital internal medicine perspectives · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maryam Amini PouyaDepartment of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Seyyedeh Maryam AfshaniDepartment of Pharmacoeconomics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Armin Salek MaghsoudiDepartment of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Shokoufeh HassaniDepartment of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. shokoufehasani@gmail.com.ORCID http://orcid.org/0000-0003-0533-2170
Kayvan MirniaChildren's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. kmirnia@sina.tums.ac.ir.
Tehran University of Medical Sciences · IRChildren's Medical Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are several types of research on the COVID-19 disease which have been conducting. It seems that prevailing over the pandemic would be achieved only by mastering over the virus pathophysiology. We tried to categorize the massive amount of available information for useful interpretation. EVIDENCE ACQUISITION: We searched databases with different keywords and search strategies that focus on virulence and pathophysiology of COVID-19. The present review has aimed to gather and categorize all implemented drugs based on the susceptible virulence mechanisms, and the pathophysiological events in the host cells, discussing and suggesting treatments.

resultsAs a result, the COVID-19 lifecycle were categorized as following steps: "Host Cell Attachment" which is mainly conducted with ACE

conclusionThe treatment protocol would be occasional based on the stage of the infection and the patient situation. The cocktail of medicines, which could affect almost all mentioned stages of COVID-19 disease, might be vital for patients with severe phenomena. The classification of the possible mechanism of medicines based on COVID-19 pathogenicity.

Indexed as

COVID-19 Drug TreatmentAnimalsCOVID-19HumansInflammationSARS-CoV-2CoronavirusesCOVID-19Drug classificationPandemicPharmaceutical agentsPossible treatmentsSARS-CoV-2

Identifiers

PMID32734518
PMCPMC7391927
OpenAlexW3046018449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.