Evidence map›Paper›PMID 32734511›Full record

ReviewCurrent osteoporosis reports2020

Biomechanics of Implant Fixation in Osteoporotic Bone.

Kyle D Anderson, Frank C Ko, Amarjit S Virdi, D Rick Sumner, Ryan D Ross

Open access · greenAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Long-term outcomes of cemented compared to uncemented femoral stems in total hip arthroplasty for displaced femoral neck fractures in elderly patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  14. Osteoporosis is not associated with increased reoperation or fracture risk three years after total ankle arthroplasty: a retrospective cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kyle D AndersonDepartment of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.ORCID 0000-0002-5312-7801
Frank C KoDepartment of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.ORCID 0000-0001-7305-7946
Amarjit S VirdiDepartment of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.ORCID 0000-0002-8834-2659
D Rick SumnerDepartment of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.ORCID 0000-0001-9575-3862
Ryan D RossDepartment of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA. ryan_ross@rush.edu.ORCID 0000-0003-3760-234X
Rush University Medical Center · US

Funding

Pre and Post-Doctoral Training in Joint HealthT32AR073157 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI D Rick Sumner · 2019 to 2026
$2.3M
Detection and Treatment of Peri-Implant OsteolysisR01AR066562 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI SUMNER, D RICK · 2015 to 2019
$1.7M
Sclerostin Regulation of Skeletal Mineralization and Phosphate MetabolismK01AR073923 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI ROSS, RYAN DEE · 2019 to 2022
$462k
Role of the Gut Microbiome in Implant LooseningR21AR075130 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI SUMNER, D RICK · 2019 to 2020
$380k
NIAMS NIH HHS K01 AR073923NIAMS NIH HHS R01 AR066562NIAMS NIH HHS R21 AR075130NIAMS NIH HHS T32 AR073157
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to critically evaluate the current literature regarding implant fixation in osteoporotic bone. RECENT

findingsClinical studies have not only demonstrated the growing prevalence of osteoporosis in patients undergoing total joint replacement (TJR) but may also indicate a significant gap in screening and treatment of this comorbidity. Osteoporosis negatively impacts bone in multiple ways beyond the mere loss of bone mass, including compromising skeletal regenerative capacity, architectural deterioration, and bone matrix quality, all of which could diminish implant fixation. Recent findings both in preclinical animal models and in clinical studies indicate encouraging results for the use of osteoporosis drugs to promote implant fixation. Implant fixation in osteoporotic bone presents an increasing clinical challenge that may be benefitted by increased screening and usage of osteoporosis drugs.

Indexed as

Bone-Implant InterfaceJoint ProsthesisProsthesis RetentionAnimalsArthroplasty, ReplacementBiomechanical PhenomenaHumansOsteoporosisProsthesis FailureFixationImplantOsteoporosisTotal joint replacement

Identifiers

PMID32734511
PMCPMC7541774
OpenAlexW3046250971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.