Evidence map›Paper›PMID 32734504›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

New technologies for intensive prevention programs after myocardial infarction: rationale and design of the NET-IPP trial.

Harm Wienbergen, Andreas Fach, Jeanette Erdmann, Alexander Katalinic, Nora Eisemann, Peter Krawitz, Carlo Maj, Oleg Borisov, Matthias Munz, Markus Noethen and 7 more

Abstract readClinical Trial Protocol
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for coronary heart disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Impact of educational attainment on preventive efforts after myocardial infarction: results of the IPP and NET-IPP trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Trial
  3. Long-term risk factor management and adverse events in patients with early-onset myocardial infarction-a "real-world" study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Harm WienbergenBremen Institute for Heart and Circulation Research at the Klinikum Links der Weser, Senator-Wessling-Str. 1, 28277, Bremen, Germany. harm.wienbergen@klinikum-bremen-ldw.de.ORCID http://orcid.org/0000-0001-5603-9391
Andreas FachBremen Institute for Heart and Circulation Research at the Klinikum Links der Weser, Senator-Wessling-Str. 1, 28277, Bremen, Germany.
Jeanette ErdmannInstitute for Cardiogenetics, Lübeck University Heart Center, Lübeck, Germany.
Alexander KatalinicInstitute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.
Nora EisemannInstitute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.
Peter KrawitzInstitute for Genomic Statistics and Bioinformatics, University Hospital of Bonn, Bonn, Germany.
Carlo MajInstitute for Genomic Statistics and Bioinformatics, University Hospital of Bonn, Bonn, Germany.
Oleg BorisovInstitute for Genomic Statistics and Bioinformatics, University Hospital of Bonn, Bonn, Germany.
Matthias MunzInstitute for Cardiogenetics, Lübeck University Heart Center, Lübeck, Germany.
Markus NoethenInstitute of Human Genetics, University Hospital of Bonn, Bonn, Germany.
Roza Meyer-SaraeiMedical Clinic II, Lübeck University Heart Center, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Rico OstereschBremen Institute for Heart and Circulation Research at the Klinikum Links der Weser, Senator-Wessling-Str. 1, 28277, Bremen, Germany.
Johannes SchmuckerBremen Institute for Heart and Circulation Research at the Klinikum Links der Weser, Senator-Wessling-Str. 1, 28277, Bremen, Germany.
Axel LinkeHeart Center, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.
Ingo EitelMedical Clinic II, Lübeck University Heart Center, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Rainer HambrechtBremen Institute for Heart and Circulation Research at the Klinikum Links der Weser, Senator-Wessling-Str. 1, 28277, Bremen, Germany.
Harald LangerMedical Clinic II, Lübeck University Heart Center, Ratzeburger Allee 160, 23538, Lübeck, Germany.
University of Lübeck · DEKlinikum Links der Weser · DEUniversity Hospital Bonn · DEUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCurrent health care data reveal suboptimal prevention in patients with coronary artery disease and an unmet need to develop effective preventive strategies. The New Technologies for Intensive Prevention Programs (NET-IPP) Trial will investigate if a long-term web-based prevention program after myocardial infarction (MI) will reduce clinical events and risk factors. In a genetic sub study the impact of disclosure of genetic risk using polygenic risk scores (PRS) will be assessed. STUDY

designPatients hospitalized for MI will be prospectively enrolled and assigned to either a 12-months web-based intensive prevention program or standard care. The web-based program will include telemetric transmission of risk factor data, e-learning and electronic contacts between a prevention assistant and the patients. The combined primary study endpoint will comprise severe adverse cardiovascular events after 2 years. Secondary endpoints will be risk factor control, adherence to medication and quality of life. In a genetic sub study genetic risk will be assessed in all patients of the web-based intensive prevention program group by PRS and patients will be randomly assigned to genetic risk disclosure vs. no disclosure. The study question will be if disclosure of genetic risk has an impact on patient motivation and cardiovascular risk factor control.

conclusionsThe randomized multicenter NET-IPP study will evaluate for the first time the effects of a long-term web-based prevention program after MI on clinical events and risk factor control. In a genetic sub study the impact of disclosure of genetic risk using PRS will be investigated.

Indexed as

FemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesQuality of LifeRandomized Controlled Trials as TopicRisk FactorsSecondary PreventionTelemetryDisclosure of genetic riskMyocardial infarctionPolygenic risk scoresWeb-based prevention program

Identifiers

PMID32734504
OpenAlexW3046022228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.