ArticleKidney medicine
Health-Related Quality of Life in Home Dialysis Patients Compared to In-Center Hemodialysis Patients: A Systematic Review and Meta-analysis.
Article in Kidney medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Perspectives of Indigenous Peoples on Home Dialysis: A Systematic Review and Meta-Synthesis of Qualitative Studies.Clinical journal of the American Society of Nephrology : CJASN · 2026Pooled it
- Home versus in-centre haemodialysis for people with kidney failure.The Cochrane database of systematic reviews · 2024Pooled it
- The effect of renal replacement therapy on health-related quality of life in end-stage renal disease: a meta-analysis.Clinical and experimental nephrology · 2023Pooled it
- Observational
- Validation of the Standardized Outcomes in Nephrology - Life Participation (SONG-LP) Instrument in People Receiving Dialysis.Kidney international reports · 2026Article
- Hospitalization Risk in the Integrated Home Dialysis Model: Analysis of the Canadian Organ Replacement Register.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Development of 'Location of Dialysis Care in Kidney Life', a service delivery intervention to eliminate unwarranted variation in home dialysis uptake between kidney services and to optimise home dialysis use.BMC health services research · 2026Article
- Integrating Algorithm-Driven Analytics and Clinical Decision Support in Remote Monitoring in Automated Peritoneal Dialysis: Patient and Clinician Experiences.Blood purification · 2026Article
- Quality of life and biochemical changes in patients undergoing kidney replacement therapy among patients with end-stage kidney disease: a cross-sectional study from Brunei Darussalam.International urology and nephrology · 2026Article
- "You Gotta Keep Climbing That Mountain to Reach the Goal": Perspectives of Transplant Waitlisted Dialysis Patients. A Qualitative Study.Kidney medicine · 2026Article
- Experiences of individuals undergoing maintenance hemodialysis during the COVID-19 pandemic in China: a qualitative study.BMC nephrology · 2025Article
- Impact of a Longitudinal Virtual Education Series on Home Dialysis Education: A Mixed-Methods Evaluation.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Outcomes of Initiating Peritoneal Dialysis versus Hemodialysis in Severe, Symptomatic Kidney Failure.Kidney360 · 2025Article
- A survey on the association between patient activation and quality of life among patients with chronic kidney disease in Japan.Journal of nephrology · 2025Observational
- Combating the rising tide of kidney advocacy in Europe: the seminal role of the European Kidney Health Alliance (EKHA).Clinical kidney journal · 2025Review
- Burden of hemodialysis on health-related quality of life: insights from a multi-center cross-sectional analysis in Southern Albania.Frontiers in medicine · 2025Article
- From Home to Wearable Hemodialysis: Barriers, Progress, and Opportunities.Clinical journal of the American Society of Nephrology : CJASN · 2024Review
- The Burden of Home Dialysis: An Overlooked Challenge.Clinical journal of the American Society of Nephrology : CJASN · 2024Review
- Home Hemodialysis Emerges as a Safe and Effective Option for Dialysis Patients amid COVID-19 Pandemic.Journal of caring sciences · 2024Article
- Transfers from home to facility-based dialysis: comparisons of HHD, assisted PD and autonomous PD.Clinical kidney journal · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RATIONALE &
objectiveDialysis patients judge health-related quality of life (HRQoL) as an essential outcome. Remarkably, little is known about HRQoL differences between home dialysis and in-center hemodialysis (HD) patients worldwide. STUDY
designSystematic review and meta-analysis. SETTING & STUDY POPULATIONS: Search strategies were performed on the Cochrane Library, Pubmed, and EMBASE databases between 2007 and 2019. Home dialysis was defined as both peritoneal dialysis and home HD. SELECTION CRITERIA FOR STUDIES: Randomized controlled trials and observational studies that compared HRQoL in home dialysis patients versus in-center HD patients. DATA EXTRACTION: The data extracted by 2 authors included HRQoL scores of different questionnaires, dialysis modality, and subcontinent. ANALYTICAL APPROACH: Data were pooled using a random-effects model and results were expressed as standardized mean difference (SMD) with 95% CIs. Heterogeneity was explored using subgroup analyses.
resultsForty-six articles reporting on 41 study populations were identified. Most studies were cross-sectional in design (90%), conducted on peritoneal dialysis patients (95%), and used the 12-item or 36-item Short-Form Health Survey questionnaires (83%). More than half the studies showed moderate or high risk of bias. Pooled analysis of 4,158 home dialysis patients and 7,854 in-center HD patients showed marginally better physical HRQoL scores in home dialysis patients compared with in-center HD patients (SMD, 0.14; 95% CI, 0.04 to 0.24), although heterogeneity was high ( LIMITATIONS: No randomized controlled trials were found and high heterogeneity among studies existed.
conclusionsAlthough pooled data showed marginally better physical HRQoL for home dialysis patients, the quality of design of the included studies was poor. Large prospective studies with adequate adjustments for confounders are necessary to establish whether home dialysis results in better HRQoL.
trial registrationPROSPERO 95985.
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