ArticleKidney medicine
The Impact of Race and Ethnicity Upon Health-Related Quality of Life and Mortality in Dialysis Patients.
Article in Kidney medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Nondialytic Care vs Dialysis Transition on Hospitalization: Outcomes in Veterans With Advanced Chronic Kidney Disease.Mayo Clinic proceedings · 2026Article
- Sleep Patterns, Symptoms, and Mortality in Hemodialysis: A Prospective Cohort Study.Kidney medicine · 2025Article
- Thyroid function analysis after roxadustat or erythropoietin treatment in patients with renal anemia: a cohort study.Renal failure · 2023Article
- A real-world analysis of the influence of age on maintenance hemodialysis patients: managing serum phosphorus with sucroferric oxyhydroxide as part of routine clinical care.International urology and nephrology · 2023Article
- Delivery of an at-home transcranial direct current stimulation intervention to mitigate pain in patients with end-stage kidney disease receiving hemodialysis (ESKD/HD).Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Predicting Hospice Transitions in Dementia Caregiving Dyads: An Exploratory Machine Learning Approach.Innovation in aging · 2022Article
- The Use of Putative Dialysis Initiation Time in Comparative Outcomes of Patients with Advanced Chronic Kidney Disease: Methodological Aspects.International journal of statistics in medical research · 2022Article
- The Interplay Between Thyroid Dysfunction and Kidney Disease.Seminars in nephrology · 2021Review
- Impact of health-related quality of life on survival after dialysis initiation: a prospective cohort study in Korea.Kidney research and clinical practice · 2020Article
- Health-related quality of life (HRQoL) associated with echinococcosis patients in Tibetan communities in Shiqu County, China: a case-control study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
RATIONALE &
objectiveHealth-related quality of life (HRQoL) has been recognized as a strong predictor of mortality among hemodialysis patients. However, differences in the association of HRQoL with survival across diverse racial/ethnic groups have not been well studied in this population. STUDY
designObservational cohort study. SETTING &
participantsWe examined the relationship between HRQoL and mortality in a prospective cohort of racially/ethnically diverse hemodialysis patients recruited from 18 outpatient dialysis units during 2011 to 2016. EXPOSURE: Using the 36-Item Short Form Health Survey (SF-36) administered every 6 months, HRQoL was ascertained by 36 questions summarized as 2 Physical and Mental Component and 8 subscale scores. OUTCOME: All-cause mortality. ANALYTICAL APPROACH: Associations of time-varying SF-36 scores with mortality were estimated using Cox models in the overall cohort and within racial/ethnic subgroups.
resultsAmong 753 hemodialysis patients who met eligibility criteria, expanded case-mix analyses showed that the lowest quartiles of time-varying Physical and Mental Component scores were associated with higher mortality in the overall cohort (reference: highest quartile): adjusted HRs, 2.30 (95% CI, 1.53-3.47) and 1.54 (95% CI, 1.05-2.25), respectively. In analyses stratified by race/ethnicity, the lowest quartile of Physical Component scores was significantly associated with higher mortality across all groups: adjusted HRs, 2.64 (95% CI, 1.31-5.29), 1.84 (95% CI, 1.01-3.38), and 3.18 (95% CI, 1.13-8.91) for Hispanic, African American, and other race/ethnicity patients, respectively. The lowest quartile of time-varying physical functioning, role limitations due to physical health, role limitations due to emotional problems, social functioning, and pain subscale scores were associated with higher mortality in the overall cohort and particularly in Hispanics and blacks. LIMITATIONS: Residual confounding cannot be excluded.
conclusionsLower SF-36 Physical Component and subscale scores were associated with higher mortality in hemodialysis patients, including those of minority background. Further studies are needed to determine whether interventions that augment physical health might improve the survival of these diverse populations.
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