Evidence map›Paper›PMID 32734158›Full record

ArticleJAMIA open2020

Experiences implementing scalable, containerized, cloud-based NLP for extracting biobank participant phenotypes at scale.

Timothy A Miller, Paul Avillach, Kenneth D Mandl

Abstract read
In one paragraph

Article in JAMIA open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The SMART Text2FHIR Pipeline.medRxiv : the preprint server for health sciences · 2023
    Article
  2. Article
  3. The SMART Text2FHIR Pipeline.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy A MillerComputational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-4513-403X
Paul AvillachComputational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Kenneth D MandlComputational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts, USA.

Funding

Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD ResearchU01HL121518 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ABMAN, STEVEN HERBERT, MANDL, KENNETH D. · 2014 to 2018
$9.3M
Instrumenting the Delivery System for a Genomics Research Information CommonsU01TR002623 · NCATS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2019 to 2024
$8.6M
Learning Universal Patient Representations with Hierarchical TransformersR01LM012973 · NLM · BOSTON CHILDREN'S HOSPITAL · PI Timothy A Miller · 2019 to 2026
$3.5M
NCATS NIH HHS U01 TR002623NHLBI NIH HHS U01 HL121518NLM NIH HHS R01 LM012973
6 · The paper itself

Abstract

objectiveTo develop scalable natural language processing (NLP) infrastructure for processing the free text in electronic health records (EHRs). MATERIALS AND

methodsWe extend the open-source Apache cTAKES NLP software with several standard technologies for scalability. We remove processing bottlenecks by monitoring component queue size. We process EHR free text for patients in the PrecisionLink Biobank at Boston Children's Hospital. The extracted concepts are made searchable via a web-based portal.

resultsWe processed over 1.2 million notes for over 8000 patients, extracting 154 million concepts. Our largest tested configuration processes over 1 million notes per day. DISCUSSION: The unique information represented by extracted NLP concepts has great potential to provide a more complete picture of patient status.

conclusionNLP large EHR document collections can be done efficiently, in service of high throughput phenotyping.

Indexed as

biobankingmedical informaticsnatural language processingphenotyping

Identifiers

PMID32734158
PMCPMC7382623

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.