ArticleDevelopment & reproduction2020
Exposure to Phthalate Esters and the Risk of Endometriosis.
Article in Development & reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Unravelling the link between phthalate exposure and endometriosis in humans: a systematic review and meta-analysis of the literature.Journal of assisted reproduction and genetics · 2021Pooled it
- An Epidemiologic Review of Endocrine-disrupting Chemicals and Understudied Gynecologic Health Conditions Affecting Quality of Life.Current environmental health reports · 2026Review
- Endocrine-disrupting chemicals and female reproductive health: a growing concern.Nature reviews. Endocrinology · 2025Review
- Exposure to phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Morin hydrate treatment minimizes Di(2-ethylhexyl) phthalate-induced uterine fibrosis, oxidative stress, and apoptosis in mice.Molecular biology reports · 2025Article
- Association between the Exposure to Phthalates and the Risk of Endometriosis: An Updated Review.Biomedicines · 2024Review
- Advances in understanding the reproductive toxicity of endocrine-disrupting chemicals in women.Frontiers in cell and developmental biology · 2024Review
- Effects of Dibutylphthalate and Steroid Hormone Mixture on Human Prostate Cells.International journal of molecular sciences · 2023Article
- Endometriosis: Update of Pathophysiology, (Epi) Genetic and Environmental Involvement.Biomedicines · 2023Review
- Association between urinary phthalate levels and chronic pain in US adults, 1999-2004: A nationally representative survey.Frontiers in neurology · 2023Article
- Medical devices as a source of phthalate exposure: a review of current knowledge and alternative solutions.Arhiv za higijenu rada i toksikologiju · 2022Review
- Di-(2-ethylhexyl) Phthalate Triggers Proliferation, Migration, Stemness, and Epithelial-Mesenchymal Transition in Human Endometrial and Endometriotic Epithelial Cells via the Transforming Growth Factor-β/Smad Signaling Pathway.International journal of molecular sciences · 2022Article
- The impact of phthalate on reproductive function in women with endometriosis.Reproductive medicine and biology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a common gynecologic disease, worldwide, whose true prevalence is uncertain because it is a difficult disease to diagnose. Endometriosis is a common cause of chronic pelvic pain, dysmenorrhea, and infertility, and is also associated with ovarian cancer. Although the risk factors for endometriosis are unclear, there is increasing evidence that exposure to environmental contaminants, especially phthalates, could affect the pathogenesis of endometriosis. Phthalates are industrial chemicals, used to make flexible plastics, and are present in numerous common plastic products, including medical devices and materials. Several
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.