Evidence map›Paper›PMID 32734075›Full record

ArticleVeterinary and animal science2019

Acceptability of flavoured pharmaceutically non-active mini-tablets in pet cats tested with a rapid 3-portal acceptance test with and without food.

S Savolainen, J Hautala, J Junnila, S Airaksinen, A M Juppo, M Raekallio, O Vainio

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary and animal science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

S SavolainenDepartment of Equine and Small Animal Medicine, University of Helsinki, P.O. Box 57, 00014 University of Helsinki, Finland.
J HautalaDivision of Pharmaceutical Chemistry and Technology, University of Helsinki, P.O. Box 56, 00014 University of Helsinki, Finland.
J Junnila4Pharma Ltd, Arkadiankatu 7, 00100 Helsinki, Finland.
S AiraksinenDivision of Pharmaceutical Chemistry and Technology, University of Helsinki, P.O. Box 56, 00014 University of Helsinki, Finland.
A M JuppoDivision of Pharmaceutical Chemistry and Technology, University of Helsinki, P.O. Box 56, 00014 University of Helsinki, Finland.
M RaekallioDepartment of Equine and Small Animal Medicine, University of Helsinki, P.O. Box 57, 00014 University of Helsinki, Finland.
O VainioDepartment of Equine and Small Animal Medicine, University of Helsinki, P.O. Box 57, 00014 University of Helsinki, Finland.
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palatable oral pharmaceuticals are crucial for feline medication. The pharmaceutical industry prefers synthetic flavours over organic ones because of hygiene and regulatory issues. The aim of this study was to find a palatable synthetic flavour for future taste-masking of feline pharmaceuticals. The hypothesis was that synthetic meat aromas and free amino acids would be palatable to cats. The palatability of 18 synthetically flavoured mini-tablets was screened with 10-19 pet cats using a rapid 3-portal acceptance test with and without food. The tested flavours were synthetic amino acids (L-carnitine, l-glutamic acid monosodium salt hydrate, l-leucine, l-methionine, l-phenylalanine, l-proline, and taurine), d-(+)-Maltose monohydrate and thiamine hydrochloride. Furthermore, thiamine hydrochloride was combined with amino acids (l-cysteine, l-leucine, l-methionine and l-proline) and synthetic meat flavours (2-acetylpyridine, 2-acetylthiazole, 2-pentylpyridine and 4-hydroxy-5-methyl-3(

Indexed as

Amino acidsCatDrug developmentPalatability testingSynthetic flavours

Identifiers

PMID32734075
PMCPMC7386771
OpenAlexW2920640884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.