Evidence map›Paper›PMID 32733937›Full record

ArticleBioMed research international2020

Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.

Chao Chen, Songming Liu, Ruokai Qu, Bo Li

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  12. Liquid Biopsy, ctDNA Diagnosis through NGS.Life (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chao ChenBGI-Shenzhen, Shenzhen 518083, China.ORCID https://orcid.org/0000-0003-0990-5239
Songming LiuBGI-Shenzhen, Shenzhen 518083, China.ORCID https://orcid.org/0000-0003-1407-1267
Ruokai QuBGI-Shenzhen, Shenzhen 518083, China.ORCID https://orcid.org/0000-0001-7262-8647
Bo LiBGI-Shenzhen, Shenzhen 518083, China.ORCID https://orcid.org/0000-0002-9199-1449
BGI Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed at investigating the mutations in colorectal cancer (CRC) for recurrent neoantigen identification. A total of 1779 samples with whole exome sequencing (WES) data were obtained from 7 published CRC cohorts. Common HLA genotypes were used to predict the probability of neoantigens at high-frequency mutants in the dataset. Based on the WES data, we not only obtained the most comprehensive CRC mutation landscape so far but also found 1550 mutations which could be identified in at least 5 patients, including

Indexed as

ImmunotherapyAmino Acid SequenceAntigens, NeoplasmCohort StudiesColorectal NeoplasmsFemaleHumansINDEL MutationMaleMiddle AgedMutationMutation RatePeptidesPolymorphism, Single NucleotideAntigens, NeoplasmPeptides

Identifiers

PMID32733937
PMCPMC7383341
OpenAlexW3042698148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.