Evidence map›Paper›PMID 32733932›Full record

ArticleBioMed research international2020

Expression of Membrane Progesterone Receptors in Eutopic and Ectopic Endometrium of Women with Endometriosis.

Edgar Ricardo Vázquez-Martínez, Claudia Bello-Alvarez, Ana Lorena Hermenegildo-Molina, Mario Solís-Paredes, Sandra Parra-Hernández, Oliver Cruz-Orozco, J Roberto Silvestri-Tomassoni, Luis F Escobar-Ponce, Luis A Hernández-López, Christian Reyes-Mayoral and 7 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  3. Unraveling the Core of Endometriosis: The Impact of Endocrine Disruptors.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Edgar Ricardo Vázquez-MartínezUnidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 11000, Mexico.
Claudia Bello-AlvarezUnidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 11000, Mexico.
Ana Lorena Hermenegildo-MolinaUnidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 11000, Mexico.
Mario Solís-ParedesDepartamento de Genética y Genómica Humana, Instituto Nacional de Perinatología, Mexico.
Sandra Parra-HernándezDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología, Mexico.
Oliver Cruz-OrozcoSubdirección de Reproducción Humana, Instituto Nacional de Perinatología, Mexico.
J Roberto Silvestri-TomassoniDepartamento de Ginecología, Instituto Nacional de Perinatología, Mexico.
Luis F Escobar-PonceCoordinación de Ginecología Laparoscópica, Instituto Nacional de Perinatología, Mexico.
Luis A Hernández-LópezDepartamento de Ginecología, Instituto Nacional de Perinatología, Mexico.
Christian Reyes-MayoralSubdirección de Reproducción Humana, Instituto Nacional de Perinatología, Mexico.
Andrea Olguín-OrtegaDepartamento de Ginecología, Instituto Nacional de Perinatología, Mexico.
Brenda Sánchez-RamírezDepartamento de Ginecología, Instituto Nacional de Perinatología, Mexico.
Mauricio Osorio-CaballeroDepartamento de Salud Sexual y Reproducción Humana, Instituto Nacional de Perinatología, Mexico.
Elizabeth García-GómezUnidad de Investigación en Reproducción Humana, Consejo Nacional de Ciencia y Tecnología (CONACyT)-Instituto Nacional de Perinatología, Ciudad de México 11000, Mexico.
Guadalupe Estrada-GutierrezDirección de Investigación, Instituto Nacional de Perinatología, Ciudad de México 11000, Mexico.
Marco CerbónUnidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 11000, Mexico.
Ignacio Camacho-ArroyoUnidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 11000, Mexico.ORCID https://orcid.org/0000-0003-2978-1253
Instituto Nacional de Perinatología · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is one of the most frequent gynecological diseases in reproductive age women, but its etiology is not completely understood. Endometriosis is characterized by progesterone resistance, which has been explained in part by a decrease in the expression of the intracellular progesterone receptor in the ectopic endometrium. Progesterone action is also mediated by nongenomic mechanisms via membrane progesterone receptors (mPRs) that belong to the class II members of the progesterone and adipoQ receptor (PAQR) family. The aim of the present study was to evaluate the expression at mRNA and protein levels of mPR members in the eutopic and ectopic endometrium of women with endometriosis. Total RNA and total protein were isolated from control endometrium (17 samples), eutopic endometrium (17 samples), and ectopic endometrium (9 samples). The expression of

Indexed as

AdultCell MembraneDown-RegulationEndometriosisEndometriumFemaleHumansMembrane ProteinsReceptors, ProgesteroneMembrane ProteinsReceptors, Progesterone

Identifiers

PMID32733932
PMCPMC7376402
OpenAlexW3043023573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.