Evidence map›Paper›PMID 32733719›Full record

ArticleCase reports in infectious diseases2020

False-Negative CSF Cryptococcal Antigen with

Shawn Esperti, Austen Stoelting, Andrew Mangano, Dveet Patel, Jilian Sansbury, Robert Sherertz

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Infections due to RareJournal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shawn EspertiDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.ORCID https://orcid.org/0000-0002-7074-3163
Austen StoeltingDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.
Andrew ManganoDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.
Dveet PatelDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.
Jilian SansburyDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.
Robert SherertzDepartment of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old immunocompetent male in South Carolina was admitted secondary to altered mental status and headache without focal neurological deficits. Head CT was negative. Lumbar puncture (LP) revealed normal glucose, elevated protein, and lymphocytosis. Opening pressure was 15 cm of H20. CSF lateral flow assay was negative for cryptococcal antigen; CSF cultures showed no growth. The patient rapidly improved on acyclovir and was diagnosed with presumed viral meningitis, as viral PCR and fungal culture were pending at time of discharge. The patient's condition quickly worsened and the patient returned one day later with right arm weakness and dysarthria. Brain MRI revealed T2/flair signal abnormalities in the left frontal lobe with associated parenchymal enhancement. Repeat LP revealed increasing white blood cell count with a worsening lymphocytosis and decreasing glucose, and opening pressure remained normal. CSF fungal culture from the first admission grew

Identifiers

PMID32733719
PMCPMC7376414
OpenAlexW4210722575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.