ReviewJournal of ophthalmology2020
Active Vision Therapy for Anisometropic Amblyopia in Children: A Systematic Review.
Review in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Efficacy of vision-based treatments for children and teens with amblyopia: a systematic review and meta-analysis of randomised controlled trials.BMJ open ophthalmology · 2021Pooled it
- Randomised trial of three treatments for amblyopia: Vision therapy and patching, perceptual learning and patching alone.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Trial
- Advances in behavioral vision training for the treatment of childhood amblyopia: a narrative review.Translational pediatrics · 2026Review
- Video Game-Based Interventions for Visual Rehabilitation in Childhood Amblyopia: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Effect of active vision therapy on contrast sensitivity in bilateral amblyopia.International journal of ophthalmology · 2026Article
- AmblyoPlay-based multimodal visual therapy in pediatric anisometropic amblyopia: a pilot study of visual, oculomotor and sensorimotor outcomes.BMC ophthalmology · 2025Article
- Rehabilitation of amblyopia using a digital platform for visual training combined with patching in children: a prospective study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Add-on perceptual learning on refractive amblyopia in children.International journal of ophthalmology · 2024Article
- Stroboscopic visual training: The potential for clinical application in neurological populations.PLOS digital health · 2023Review
- Quantitative evaluation of anisometropic amblyopia treatment efficacy by coupling multiple visual functions via CRITIC algorithm.BMC ophthalmology · 2023Article
- Artificial intelligence-based screening for amblyopia and its risk factors: comparison with four classic stereovision tests.Frontiers in medicine · 2023Article
- Vision Therapy: A Primer and Caution for Pediatricians.Children (Basel, Switzerland) · 2022Article
- Long-Term Efficacy of the Combination of Active Vision Therapy and Occlusion in Children with Strabismic and Anisometropic Amblyopia.Children (Basel, Switzerland) · 2022Article
- Study protocol for a randomized controlled trial of the NEIVATECH virtual reality system to improve visual function in children with anisometropic amblyopia.BMC ophthalmology · 2022Article
- Effects of Vision Therapy on Bilateral Amblyopia Unresponsive to Conventional Treatment: A Retrospective Comparative Study.Children (Basel, Switzerland) · 2022Article
- Efficacy of vision therapy for unilateral refractive amblyopia in children aged 7-10 years.BMC ophthalmology · 2022Article
- The Study of Short-Term Plastic Visual Perceptual Training Based on Virtual and Augmented Reality Technology in Amblyopia.Journal of ophthalmology · 2022Article
- Efficacy of Perceptual Learning-Based Vision Training as an Adjuvant to Occlusion Therapy in the Management of Amblyopia: A Pilot Study.Vision (Basel, Switzerland) · 2021Article
- Stimuli Characteristics and Psychophysical Requirements for Visual Training in Amblyopia: A Narrative Review.Journal of clinical medicine · 2020Review
- Characterization, passive and active treatment in strabismic amblyopia: a narrative review.International journal of ophthalmology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the study was evaluation of the scientific evidence about the efficacy of vision therapy in children and teenagers with anisometropic amblyopia by performing a systematic literature review.
methodsA search was performed using 3 searching strategies in 4 different databases (PubMed, Web of Science, Scopus, and PruQuest). The quality of the included articles was evaluated using two tools for the risk of bias assessment, ROBINS-I for nonrandomized studies of intervention (NRSI), and ROB 2.0 for randomized clinical trials.
resultsThe search showed 1274 references, but only 8 of them passed the inclusion criteria after the complete text review. The articles that were finally included comprised 2 randomized control trials and 6 nonrandomized studies of intervention. These articles provided evidence supporting the efficacy of vision therapy for the treatment of anisometropic amblyopia in children and teenagers. Assessment of the risk of bias showed an appropriate risk of bias for the randomized control trials, but a high risk of bias for nonrandomized studies of intervention (NRSI). A main source of risk of bias for NRSI was the domain related to the measurements of the outcomes, due to a lack of double-blind studies.
conclusionVision therapy is a promising option for the treatment of anisometropic amblyopia in children and teenagers. However, the level of scientific evidence provided by the studies revised is still limited, and further randomized clinical trials are necessary to confirm the results provided to date and to optimize the vision therapy techniques by knowing the specific neural mechanisms involved.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.