ArticleOxidative medicine and cellular longevity2020
Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan of
Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Identification of active anti-aging ingredients from asparagus cochinchinensis based on the spectrum-effect relationship.BMC complementary medicine and therapies · 2025Article
- A comprehensive review on the anti-cancer properties of sesame lignans: chemical composition, molecular mechanisms and prospects.RSC advances · 2025Review
- A Ginsenoside Composition Ameliorated Aβ and Tau Aggregation via Autophagy Lysosome Pathway.Molecular neurobiology · 2025Article
- Evaluation of Product Yield and Fatty Acid Composition of Three Flax (Life (Basel, Switzerland) · 2025Article
- Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway.Scientific reports · 2025Article
- Article
- Flavonoids and Other Polyphenols: Bioactive Molecules from Traditional Medicine Recipes/Medicinal Plants and Their Potential for Phytopharmaceutical and Medical Application.Molecules (Basel, Switzerland) · 2024Review
- Secoisolariciresinol diglucoside attenuates neuroinflammation and cognitive impairment in female Alzheimer's disease mice via modulating gut microbiota metabolism and GPER/CREB/BDNF pathway.Journal of neuroinflammation · 2024Article
- Jujubae Fructus extract prolongs lifespan and improves stress tolerance in Caenorhabditis elegans dependent on DAF-16/SOD-3.Scientific reports · 2024Article
- Fatty Acid Release and Gastrointestinal Oxidation Status: Different Methods of Processing Flaxseed.Foods (Basel, Switzerland) · 2024Article
- Melatonin derivative 6a as a PARP-1 inhibitor for the treatment of Parkinson's disease.Frontiers in pharmacology · 2024Article
- Downregulation of hnRNPA1 inhibits hepatocellular carcinoma cell progression by modulating alternative splicing of ZNF207 exon 9.Frontiers in oncology · 2024Article
- Effect of germination pretreatment on the physicochemical properties and lipid concomitants of flaxseed oil.RSC advances · 2023Article
- Article
- Orientin Prolongs the Longevity ofOxidative medicine and cellular longevity · 2022Article
- Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials inMolecules (Basel, Switzerland) · 2021Review
- Ginsenoside Prolongs the Lifespan ofInternational journal of molecular sciences · 2021Article
- Potential Health Benefits of Plant Food-Derived Bioactive Components: An Overview.Foods (Basel, Switzerland) · 2021Review
- Rebaudioside A Enhances Resistance to Oxidative Stress and Extends Lifespan and Healthspan inAntioxidants (Basel, Switzerland) · 2021Article
- Trigonelline Extends the Lifespan ofOxidative medicine and cellular longevity · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secoisolariciresinol diglucoside (SDG) is a phytoestrogen and rich in food flaxseed, sunflower seeds, and sesame seeds. Among the beneficial pharmacological activities of SDG on health, many are age related, such as anticancer, antidiabetes, antioxidant, and neuroprotective effects. Thus, we investigated if SDG had an effect on antiaging in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.