Evidence map›Paper›PMID 32733610›Full record

ReviewBeilstein journal of organic chemistry2020

Pauson-Khand reaction of fluorinated compounds.

Jorge Escorihuela, Daniel M Sedgwick, Alberto Llobat, Mercedes Medio-Simón, Pablo Barrio, Santos Fustero

Open access · diamondAbstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jorge Escorihuela *Departamento de Química Orgánica, Facultad de Farmacia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.ORCID https://orcid.org/0000-0001-6756-0991
Daniel M Sedgwick *Departamento de Química Orgánica, Facultad de Farmacia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.ORCID https://orcid.org/0000-0003-3902-6171
Alberto LlobatDepartamento de Química Orgánica, Facultad de Farmacia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.
Mercedes Medio-SimónDepartamento de Química Orgánica, Facultad de Farmacia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.ORCID https://orcid.org/0000-0001-9149-9350
Pablo BarrioDepartmento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Av. Julián Clavería 8, Campus Universitario de El Cristo, 33006 Oviedo, Spain.ORCID https://orcid.org/0000-0001-7101-4037
Santos FusteroDepartamento de Química Orgánica, Facultad de Farmacia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.ORCID https://orcid.org/0000-0002-7575-9439
Universitat de València · ESUniversidad de Oviedo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Pauson-Khand reaction (PKR) is one of the key methods for the construction of cyclopentenone derivatives, which can in turn undergo diverse chemical transformations to yield more complex biologically active molecules. Despite the increasing availability of fluorinated building blocks and methodologies to incorporate fluorine in compounds with biological interest, there have been few significant advances focused on the fluoro-Pauson-Khand reaction, both in the inter- and intramolecular versions. Furthermore, the use of vinyl fluorides as olefinic counterparts had been completely overlooked. In this review, we collect the advances both on the stoichiometric and catalytic intermolecular and intramolecular fluoro-Pauson-Khand reaction, with special attention to the PKR of enynes containing a fluoride moiety.

Indexed as

alkenealkyneenynefluorinePauson–Khand

Identifiers

PMID32733610
PMCPMC7372243
OpenAlexW3042920141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.